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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM49
All Species:
35.45
Human Site:
Y224
Identified Species:
97.5
UniProt:
Q96GC9
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96GC9
NP_112200.2
406
46238
Y224
A
E
P
D
D
E
E
Y
Q
E
F
E
E
M
L
Chimpanzee
Pan troglodytes
XP_001136943
419
47506
Y224
A
E
P
D
D
E
E
Y
Q
E
F
E
E
M
L
Rhesus Macaque
Macaca mulatta
XP_001109103
406
46196
Y224
A
E
P
D
D
E
E
Y
Q
E
F
E
E
M
L
Dog
Lupus familis
XP_548240
606
68076
Y424
A
E
P
D
D
E
E
Y
Q
E
F
E
E
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99KU0
406
45942
Y224
A
E
P
D
D
E
E
Y
Q
E
F
E
E
M
L
Rat
Rattus norvegicus
Q91ZQ0
406
45882
Y224
A
E
P
D
D
E
E
Y
Q
E
F
E
E
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415880
406
46341
Y224
A
E
P
D
D
E
E
Y
Q
E
F
E
E
M
L
Frog
Xenopus laevis
Q6INE8
406
46087
Y224
V
E
T
D
D
E
E
Y
A
E
F
E
E
M
L
Zebra Danio
Brachydanio rerio
Q6NYY9
406
45687
Y224
A
D
P
D
D
E
D
Y
E
E
F
E
E
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
99
64.3
N.A.
94
94.8
N.A.
N.A.
85.4
81.5
73.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.9
99.2
65.6
N.A.
97.5
97
N.A.
N.A.
93.3
89.9
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
80
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
80
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
89
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
100
100
0
12
0
0
0
0
0
0
0
0
% D
% Glu:
0
89
0
0
0
100
89
0
12
100
0
100
100
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
89
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
78
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _