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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDXP All Species: 9.7
Human Site: S185 Identified Species: 15.24
UniProt: Q96GD0 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96GD0 NP_064711.1 296 31698 S185 R D P W H P L S D G S R T P G
Chimpanzee Pan troglodytes XP_001162359 321 34104 E207 M D N R L P L E N G R F I A G
Rhesus Macaque Macaca mulatta XP_001084229 453 47893 E339 M D N R L P L E N G R F I A G
Dog Lupus familis XP_538386 703 77033 A592 P S E A A T P A E D M A R R S
Cat Felis silvestris
Mouse Mus musculus P60487 292 31493 S181 R D P W H P L S D G S R T P G
Rat Rattus norvegicus Q8VD52 309 33096 T181 R D P W H P L T D G S R T P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516666 109 11651
Chicken Gallus gallus Q5F4B1 312 32977 E198 R D N R L P L E G G S A I P G
Frog Xenopus laevis Q3B8E3 270 29197 E159 G K G R Y Y K E T D G L K L D
Zebra Danio Brachydanio rerio Q5BJJ5 262 28527 K151 H K A R Y Y K K K D G L A L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193132 306 34200 N193 D Q Q F P M R N S E L I M P G
Poplar Tree Populus trichocarpa XP_002329961 304 33492 V193 I A T N R D A V G H M T D L Q
Maize Zea mays NP_001130178 306 33994 T195 I A T N R D P T G H M T S A Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199587 301 32993 V189 I A T N R D A V G H M T D L Q
Baker's Yeast Sacchar. cerevisiae P19881 312 34606 Q201 N V D S T F P Q K G Y T F P G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.4 32.8 28 N.A. 91.2 88.3 N.A. 31.7 51.2 25.6 26.6 N.A. N.A. N.A. N.A. 37.9
Protein Similarity: 100 59.8 44.1 33.4 N.A. 94.2 91.9 N.A. 34.1 60.9 42.9 41.8 N.A. N.A. N.A. N.A. 56.2
P-Site Identity: 100 33.3 33.3 0 N.A. 100 93.3 N.A. 0 53.3 0 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 40 40 13.3 N.A. 100 100 N.A. 0 53.3 6.6 13.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: 35.2 35.2 N.A. 34.8 31.4 N.A.
Protein Similarity: 55.5 57.8 N.A. 56.1 48.4 N.A.
P-Site Identity: 0 0 N.A. 0 20 N.A.
P-Site Similarity: 0 13.3 N.A. 0 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 7 7 7 0 14 7 0 0 0 14 7 20 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 40 7 0 0 20 0 0 20 20 0 0 14 0 7 % D
% Glu: 0 0 7 0 0 0 0 27 7 7 0 0 0 0 0 % E
% Phe: 0 0 0 7 0 7 0 0 0 0 0 14 7 0 0 % F
% Gly: 7 0 7 0 0 0 0 0 27 47 14 0 0 0 60 % G
% His: 7 0 0 0 20 0 0 0 0 20 0 0 0 0 0 % H
% Ile: 20 0 0 0 0 0 0 0 0 0 0 7 20 0 0 % I
% Lys: 0 14 0 0 0 0 14 7 14 0 0 0 7 0 0 % K
% Leu: 0 0 0 0 20 0 40 0 0 0 7 14 0 27 0 % L
% Met: 14 0 0 0 0 7 0 0 0 0 27 0 7 0 0 % M
% Asn: 7 0 20 20 0 0 0 7 14 0 0 0 0 0 0 % N
% Pro: 7 0 20 0 7 40 20 0 0 0 0 0 0 40 0 % P
% Gln: 0 7 7 0 0 0 0 7 0 0 0 0 0 0 20 % Q
% Arg: 27 0 0 34 20 0 7 0 0 0 14 20 7 7 0 % R
% Ser: 0 7 0 7 0 0 0 14 7 0 27 0 7 0 7 % S
% Thr: 0 0 20 0 7 7 0 14 7 0 0 27 20 0 0 % T
% Val: 0 7 0 0 0 0 0 14 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 14 14 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _