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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDXP All Species: 19.7
Human Site: T176 Identified Species: 30.95
UniProt: Q96GD0 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96GD0 NP_064711.1 296 31698 T176 P E C L L V A T D R D P W H P
Chimpanzee Pan troglodytes XP_001162359 321 34104 T198 P G C L L V G T N M D N R L P
Rhesus Macaque Macaca mulatta XP_001084229 453 47893 T330 P D C L L V G T N M D N R L P
Dog Lupus familis XP_538386 703 77033 R583 P A S P K V S R T P S E A A T
Cat Felis silvestris
Mouse Mus musculus P60487 292 31493 T172 P D C L L V A T D R D P W H P
Rat Rattus norvegicus Q8VD52 309 33096 T172 P D C L L V A T D R D P W H P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516666 109 11651
Chicken Gallus gallus Q5F4B1 312 32977 T189 P D C L L V G T N R D N R L P
Frog Xenopus laevis Q3B8E3 270 29197 S150 L Q K P V L I S L G K G R Y Y
Zebra Danio Brachydanio rerio Q5BJJ5 262 28527 A142 L D G A P L I A I H K A R Y Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193132 306 34200 N184 N S V F I G T N I D Q Q F P M
Poplar Tree Populus trichocarpa XP_002329961 304 33492 L184 I R E N P G C L F I A T N R D
Maize Zea mays NP_001130178 306 33994 L186 I S E N P D C L F I A T N R D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199587 301 32993 L180 V R E N P G C L F I A T N R D
Baker's Yeast Sacchar. cerevisiae P19881 312 34606 G192 K D S V H F V G T N V D S T F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.4 32.8 28 N.A. 91.2 88.3 N.A. 31.7 51.2 25.6 26.6 N.A. N.A. N.A. N.A. 37.9
Protein Similarity: 100 59.8 44.1 33.4 N.A. 94.2 91.9 N.A. 34.1 60.9 42.9 41.8 N.A. N.A. N.A. N.A. 56.2
P-Site Identity: 100 53.3 53.3 13.3 N.A. 93.3 93.3 N.A. 0 60 0 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 60 66.6 20 N.A. 100 100 N.A. 0 73.3 33.3 20 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: 35.2 35.2 N.A. 34.8 31.4 N.A.
Protein Similarity: 55.5 57.8 N.A. 56.1 48.4 N.A.
P-Site Identity: 0 0 N.A. 0 0 N.A.
P-Site Similarity: 0 0 N.A. 0 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 0 0 20 7 0 0 20 7 7 7 0 % A
% Cys: 0 0 40 0 0 0 20 0 0 0 0 0 0 0 0 % C
% Asp: 0 40 0 0 0 7 0 0 20 7 40 7 0 0 20 % D
% Glu: 0 7 20 0 0 0 0 0 0 0 0 7 0 0 0 % E
% Phe: 0 0 0 7 0 7 0 0 20 0 0 0 7 0 7 % F
% Gly: 0 7 7 0 0 20 20 7 0 7 0 7 0 0 0 % G
% His: 0 0 0 0 7 0 0 0 0 7 0 0 0 20 0 % H
% Ile: 14 0 0 0 7 0 14 0 14 20 0 0 0 0 0 % I
% Lys: 7 0 7 0 7 0 0 0 0 0 14 0 0 0 0 % K
% Leu: 14 0 0 40 40 14 0 20 7 0 0 0 0 20 0 % L
% Met: 0 0 0 0 0 0 0 0 0 14 0 0 0 0 7 % M
% Asn: 7 0 0 20 0 0 0 7 20 7 0 20 20 0 0 % N
% Pro: 47 0 0 14 27 0 0 0 0 7 0 20 0 7 40 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 7 7 0 0 0 % Q
% Arg: 0 14 0 0 0 0 0 7 0 27 0 0 34 20 0 % R
% Ser: 0 14 14 0 0 0 7 7 0 0 7 0 7 0 0 % S
% Thr: 0 0 0 0 0 0 7 40 14 0 0 20 0 7 7 % T
% Val: 7 0 7 7 7 47 7 0 0 0 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 14 14 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _