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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDXP All Species: 1.05
Human Site: T291 Identified Species: 1.65
UniProt: Q96GD0 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96GD0 NP_064711.1 296 31698 T291 V E S I A D L T E G L E D _ _
Chimpanzee Pan troglodytes XP_001162359 321 34104 A313 D F Y V D S I A D L L P A L Q
Rhesus Macaque Macaca mulatta XP_001084229 453 47893 A445 D F Y V D S I A D L L P A L Q
Dog Lupus familis XP_538386 703 77033 M698 V E S I A D L M E G L E D _ _
Cat Felis silvestris
Mouse Mus musculus P60487 292 31493 M287 V E S I A D L M E G L E D _ _
Rat Rattus norvegicus Q8VD52 309 33096 M287 V E S I A D L M E G L G G L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516666 109 11651 I104 V D S I A D L I A G L E D _ _
Chicken Gallus gallus Q5F4B1 312 32977 A304 D Y Y V D S I A D L L P A L E
Frog Xenopus laevis Q3B8E3 270 29197 S265 A V D I L L A S Q D C N Q _ _
Zebra Danio Brachydanio rerio Q5BJJ5 262 28527 H257 A V N Y I L D H L L G S K _ _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193132 306 34200 G299 D L Y I E S I G H L G K L L D
Poplar Tree Populus trichocarpa XP_002329961 304 33492 L299 T S Q V S D L L H L L G P _ _
Maize Zea mays NP_001130178 306 33994 V301 T N S V Y D L V G L L Q K _ _
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199587 301 32993 I295 T S T V S D I I K L M E S P _
Baker's Yeast Sacchar. cerevisiae P19881 312 34606 L307 K L G D I Y T L T N N E L _ _
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.4 32.8 28 N.A. 91.2 88.3 N.A. 31.7 51.2 25.6 26.6 N.A. N.A. N.A. N.A. 37.9
Protein Similarity: 100 59.8 44.1 33.4 N.A. 94.2 91.9 N.A. 34.1 60.9 42.9 41.8 N.A. N.A. N.A. N.A. 56.2
P-Site Identity: 100 6.6 6.6 92.3 N.A. 92.3 66.6 N.A. 76.9 6.6 7.6 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 26.6 26.6 92.3 N.A. 92.3 66.6 N.A. 84.6 26.6 23 7.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 35.2 35.2 N.A. 34.8 31.4 N.A.
Protein Similarity: 55.5 57.8 N.A. 56.1 48.4 N.A.
P-Site Identity: 23 30.7 N.A. 14.2 7.6 N.A.
P-Site Similarity: 38.4 46.1 N.A. 57.1 7.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 0 34 0 7 20 7 0 0 0 20 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % C
% Asp: 27 7 7 7 20 54 7 0 20 7 0 0 27 0 7 % D
% Glu: 0 27 0 0 7 0 0 0 27 0 0 40 0 0 7 % E
% Phe: 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 0 0 0 0 7 7 34 14 14 7 0 0 % G
% His: 0 0 0 0 0 0 0 7 14 0 0 0 0 0 0 % H
% Ile: 0 0 0 47 14 0 34 14 0 0 0 0 0 0 0 % I
% Lys: 7 0 0 0 0 0 0 0 7 0 0 7 14 0 0 % K
% Leu: 0 14 0 0 7 14 47 14 7 54 67 0 14 34 0 % L
% Met: 0 0 0 0 0 0 0 20 0 0 7 0 0 0 0 % M
% Asn: 0 7 7 0 0 0 0 0 0 7 7 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 20 7 7 0 % P
% Gln: 0 0 7 0 0 0 0 0 7 0 0 7 7 0 14 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 14 40 0 14 27 0 7 0 0 0 7 7 0 7 % S
% Thr: 20 0 7 0 0 0 7 7 7 0 0 0 0 0 0 % T
% Val: 34 14 0 40 0 0 0 7 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 27 7 7 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 60 67 % _