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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKB
All Species:
23.94
Human Site:
S45
Identified Species:
40.51
UniProt:
Q96GD4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96GD4
NP_004208.2
344
39280
S45
A
L
V
L
M
S
R
S
N
V
Q
P
T
A
A
Chimpanzee
Pan troglodytes
XP_511856
395
44529
C96
A
L
V
L
M
S
R
C
N
V
Q
P
T
A
A
Rhesus Macaque
Macaca mulatta
XP_001118154
562
62706
S263
A
L
V
L
M
S
R
S
N
V
Q
P
T
A
A
Dog
Lupus familis
XP_849906
346
39574
S45
A
L
V
L
M
S
R
S
N
G
Q
P
T
A
A
Cat
Felis silvestris
Mouse
Mus musculus
O70126
345
39306
S45
A
L
A
L
V
N
R
S
N
S
Q
S
T
A
A
Rat
Rattus norvegicus
O55099
343
39216
S45
A
Q
A
L
M
N
R
S
N
S
Q
S
T
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
N45
L
G
K
G
K
F
G
N
V
Y
L
A
R
E
K
Chicken
Gallus gallus
XP_425725
409
46456
S115
Q
A
P
V
P
A
K
S
S
E
A
D
S
V
S
Frog
Xenopus laevis
Q6DE08
361
41717
S61
R
I
T
P
S
A
S
S
S
V
P
G
R
V
A
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
S45
R
V
P
V
K
S
N
S
K
V
L
S
I
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
S49
Y
G
Q
P
Y
D
W
S
P
R
D
F
E
M
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01427
305
34731
T49
G
S
V
Y
L
A
R
T
K
T
G
H
F
H
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M077
294
33954
F42
K
P
L
G
R
G
K
F
G
H
V
Y
L
A
R
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
S72
K
F
L
D
M
E
S
S
K
I
P
S
P
I
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
60.3
91.3
N.A.
84.9
84.5
N.A.
61.9
56.9
67.5
66.5
N.A.
44.4
N.A.
53.4
N.A.
Protein Similarity:
100
86.3
60.6
95
N.A.
91.5
90.4
N.A.
72
66.5
78.6
76.1
N.A.
62.5
N.A.
65.1
N.A.
P-Site Identity:
100
93.3
100
93.3
N.A.
66.6
60
N.A.
0
6.6
20
20
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
93.3
100
93.3
N.A.
80
66.6
N.A.
6.6
46.6
40
33.3
N.A.
6.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.9
36.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68
59.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
8
15
0
0
22
0
0
0
0
8
8
0
50
43
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
0
0
0
0
8
8
0
8
8
% D
% Glu:
0
0
0
0
0
8
0
0
0
8
0
0
8
8
0
% E
% Phe:
0
8
0
0
0
8
0
8
0
0
0
8
8
0
0
% F
% Gly:
8
15
0
15
0
8
8
0
8
8
8
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
8
0
8
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
8
0
0
8
8
0
% I
% Lys:
15
0
8
0
15
0
15
0
22
0
0
0
0
0
8
% K
% Leu:
8
36
15
43
8
0
0
0
0
0
15
0
8
0
0
% L
% Met:
0
0
0
0
43
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
15
8
8
43
0
0
0
0
0
0
% N
% Pro:
0
8
15
15
8
0
0
0
8
0
15
29
8
0
0
% P
% Gln:
8
8
8
0
0
0
0
0
0
0
43
0
0
0
0
% Q
% Arg:
15
0
0
0
8
0
50
0
0
8
0
0
15
0
15
% R
% Ser:
0
8
0
0
8
36
15
72
15
15
0
29
8
0
8
% S
% Thr:
0
0
8
0
0
0
0
8
0
8
0
0
43
0
0
% T
% Val:
0
8
36
15
8
0
0
0
8
36
8
0
0
15
15
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
8
0
0
0
0
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _