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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC45
All Species:
12.73
Human Site:
Y282
Identified Species:
35
UniProt:
Q96GE4
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96GE4
NP_612372.1
821
95297
Y282
P
C
P
I
G
K
E
Y
L
H
S
S
H
C
S
Chimpanzee
Pan troglodytes
XP_001161631
821
95225
Y282
P
C
P
I
G
K
E
Y
L
H
S
S
H
C
S
Rhesus Macaque
Macaca mulatta
XP_001116599
821
95606
Y282
P
C
P
I
G
K
E
Y
L
H
S
S
H
C
P
Dog
Lupus familis
XP_537590
1084
124708
Y547
P
C
P
I
G
K
E
Y
L
R
S
S
H
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVV7
827
95138
K280
R
A
P
C
P
I
G
K
E
Y
L
W
S
S
R
Rat
Rattus norvegicus
Q5XI03
821
94489
K278
R
A
P
C
P
I
G
K
E
Y
L
C
S
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510757
867
99724
A321
L
G
E
P
I
R
P
A
I
P
L
Q
P
P
Y
Chicken
Gallus gallus
XP_415671
762
88335
G277
L
E
T
Q
T
S
E
G
V
S
G
A
L
L
S
Frog
Xenopus laevis
NP_001087738
889
102391
F341
P
C
Q
K
K
V
A
F
R
T
L
P
D
I
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.4
61.7
N.A.
72.6
71.9
N.A.
48.4
44.3
41.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
96.7
66.6
N.A.
81.1
81.1
N.A.
64
62.7
59.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
6.6
6.6
N.A.
0
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
13.3
13.3
N.A.
13.3
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
23
0
0
0
0
12
12
0
0
0
12
0
0
0
% A
% Cys:
0
56
0
23
0
0
0
0
0
0
0
12
0
34
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% D
% Glu:
0
12
12
0
0
0
56
0
23
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
0
45
0
23
12
0
0
12
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
34
0
0
45
0
12
% H
% Ile:
0
0
0
45
12
23
0
0
12
0
0
0
0
23
0
% I
% Lys:
0
0
0
12
12
45
0
23
0
0
0
0
0
0
0
% K
% Leu:
23
0
0
0
0
0
0
0
45
0
45
0
12
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
56
0
67
12
23
0
12
0
0
12
0
12
12
12
12
% P
% Gln:
0
0
12
12
0
0
0
0
0
0
0
12
0
0
0
% Q
% Arg:
23
0
0
0
0
12
0
0
12
12
0
0
0
0
23
% R
% Ser:
0
0
0
0
0
12
0
0
0
12
45
45
23
12
45
% S
% Thr:
0
0
12
0
12
0
0
0
0
12
0
0
0
0
0
% T
% Val:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
45
0
23
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _