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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF185
All Species:
17.88
Human Site:
S35
Identified Species:
39.33
UniProt:
Q96GF1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96GF1
NP_001129296.1
192
20459
S35
G
E
S
G
G
Q
D
S
T
F
E
C
N
I
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110905
143
15684
C13
G
D
S
G
S
W
P
C
L
H
Q
W
L
E
T
Dog
Lupus familis
XP_860897
186
20490
R35
N
I
C
L
E
T
A
R
E
A
V
V
S
V
C
Cat
Felis silvestris
Mouse
Mus musculus
Q91YT2
192
20502
S35
G
E
S
G
G
Q
D
S
T
F
E
C
N
I
C
Rat
Rattus norvegicus
Q568Y3
192
20475
S35
G
E
S
G
G
Q
D
S
T
F
E
C
N
I
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505788
192
20619
S35
G
E
S
S
N
Q
D
S
T
F
E
C
N
I
C
Chicken
Gallus gallus
Q5ZIR9
194
20810
N37
G
D
N
T
N
Q
D
N
T
F
E
C
N
I
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PC78
194
20501
S37
G
G
G
G
A
Q
D
S
T
F
E
C
N
I
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392285
182
20533
T36
E
C
N
I
C
L
D
T
A
K
N
A
V
I
S
Nematode Worm
Caenorhab. elegans
Q09463
235
24896
C41
K
D
A
V
V
S
L
C
G
H
L
F
C
W
P
Sea Urchin
Strong. purpuratus
XP_785402
187
20655
V45
D
T
A
K
D
A
V
V
S
R
C
G
H
L
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
72.4
60.4
N.A.
98.4
98.9
N.A.
94.7
92.7
N.A.
87.6
N.A.
N.A.
62.5
45.5
68.7
Protein Similarity:
100
N.A.
72.9
70.3
N.A.
98.9
98.9
N.A.
96.3
95.8
N.A.
91.7
N.A.
N.A.
71.3
54
79.1
P-Site Identity:
100
N.A.
20
6.6
N.A.
100
100
N.A.
86.6
66.6
N.A.
80
N.A.
N.A.
13.3
0
0
P-Site Similarity:
100
N.A.
33.3
20
N.A.
100
100
N.A.
86.6
86.6
N.A.
80
N.A.
N.A.
26.6
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
10
10
10
0
10
10
0
10
0
0
0
% A
% Cys:
0
10
10
0
10
0
0
19
0
0
10
55
10
0
64
% C
% Asp:
10
28
0
0
10
0
64
0
0
0
0
0
0
0
0
% D
% Glu:
10
37
0
0
10
0
0
0
10
0
55
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
55
0
10
0
0
10
% F
% Gly:
64
10
10
46
28
0
0
0
10
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
19
0
0
10
0
0
% H
% Ile:
0
10
0
10
0
0
0
0
0
0
0
0
0
64
0
% I
% Lys:
10
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
10
10
0
10
0
10
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
19
0
19
0
0
10
0
0
10
0
55
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
55
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% R
% Ser:
0
0
46
10
10
10
0
46
10
0
0
0
10
0
10
% S
% Thr:
0
10
0
10
0
10
0
10
55
0
0
0
0
0
10
% T
% Val:
0
0
0
10
10
0
10
10
0
0
10
10
10
10
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
10
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _