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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRMT2B All Species: 13.64
Human Site: S294 Identified Species: 30
UniProt: Q96GJ1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96GJ1 NP_079193.2 504 56476 S294 T R C S H Q Q S P Y Q L L F G
Chimpanzee Pan troglodytes XP_521176 519 58108 S294 T R C S H Q Q S P Y Q L L F G
Rhesus Macaque Macaca mulatta XP_001091317 504 56428 S294 T R C S H Q Q S P Y Q L L F G
Dog Lupus familis XP_534759 667 72765 L423 K T P S Q E G L P L E H V A G
Cat Felis silvestris
Mouse Mus musculus Q8BQJ6 493 55457 S283 T R C S H Q Q S P Y Q L L F G
Rat Rattus norvegicus NP_001011895 615 67858 L373 K T P S Q E G L P L E H M A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513281 481 53523 Q274 S H R Q S P Y Q L L S G E P Y
Chicken Gallus gallus XP_420190 478 53184 V283 E P H I F E D V L D L R F R I
Frog Xenopus laevis NP_001093345 612 69426 L386 K S P L L E D L P V E H V A G
Zebra Danio Brachydanio rerio A4QP75 473 53154 V278 Q T H I Y E E V L G F K F R I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L7S3 809 89004 E507 S D N G T D Q E Q T T N V L T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.7 95 31.4 N.A. 74.8 34.1 N.A. 65.6 57.7 33.8 51.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.1 97.4 44.8 N.A. 83.3 47.9 N.A. 76.5 74.5 48.6 66.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 20 N.A. 100 20 N.A. 0 0 13.3 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 40 N.A. 100 40 N.A. 6.6 6.6 33.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 25 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 28 0 % A
% Cys: 0 0 37 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 10 19 0 0 10 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 46 10 10 0 0 28 0 10 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 10 0 19 37 0 % F
% Gly: 0 0 0 10 0 0 19 0 0 10 0 10 0 0 64 % G
% His: 0 10 19 0 37 0 0 0 0 0 0 28 0 0 0 % H
% Ile: 0 0 0 19 0 0 0 0 0 0 0 0 0 0 19 % I
% Lys: 28 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % K
% Leu: 0 0 0 10 10 0 0 28 28 28 10 37 37 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 10 28 0 0 10 0 0 64 0 0 0 0 10 0 % P
% Gln: 10 0 0 10 19 37 46 10 10 0 37 0 0 0 0 % Q
% Arg: 0 37 10 0 0 0 0 0 0 0 0 10 0 19 0 % R
% Ser: 19 10 0 55 10 0 0 37 0 0 10 0 0 0 0 % S
% Thr: 37 28 0 0 10 0 0 0 0 10 10 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 19 0 10 0 0 28 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 10 0 0 37 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _