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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TOE1
All Species:
7.88
Human Site:
S358
Identified Species:
19.26
UniProt:
Q96GM8
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96GM8
NP_079353.3
510
56548
S358
N
L
P
G
T
Q
T
S
G
E
A
K
D
G
P
Chimpanzee
Pan troglodytes
XP_513124
565
63074
S413
N
L
P
G
T
Q
T
S
G
E
A
K
D
G
P
Rhesus Macaque
Macaca mulatta
XP_001101649
204
23337
E67
K
R
Q
P
D
K
G
E
H
S
Y
L
A
Q
V
Dog
Lupus familis
XP_532601
510
56323
S358
G
L
P
G
K
Q
T
S
E
E
N
E
D
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2E2
511
56853
L359
S
Q
P
G
T
Q
T
L
A
E
A
E
D
G
P
Rat
Rattus norvegicus
NP_001100150
393
44290
G256
R
K
C
E
R
E
N
G
K
Q
R
A
A
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422434
534
59701
E370
D
G
R
P
R
E
E
E
N
S
T
A
M
E
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923913
483
54011
K336
T
C
S
S
P
Q
G
K
R
T
H
F
E
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496602
490
55843
N338
D
L
Q
R
I
K
E
N
K
K
A
F
K
R
K
Sea Urchin
Strong. purpuratus
XP_791390
492
54720
A349
N
R
N
Q
E
V
D
A
A
N
D
T
E
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.3
40
88.6
N.A.
81.5
66.4
N.A.
N.A.
55.8
N.A.
52.3
N.A.
N.A.
N.A.
28
31.1
Protein Similarity:
100
89
40
93.3
N.A.
88.4
71.3
N.A.
N.A.
73
N.A.
67.4
N.A.
N.A.
N.A.
45.6
48.4
P-Site Identity:
100
100
0
66.6
N.A.
66.6
6.6
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
100
6.6
73.3
N.A.
80
20
N.A.
N.A.
20
N.A.
13.3
N.A.
N.A.
N.A.
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
20
0
40
20
20
0
20
% A
% Cys:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
0
10
0
10
0
0
0
10
0
40
0
0
% D
% Glu:
0
0
0
10
10
20
20
20
10
40
0
20
20
20
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% F
% Gly:
10
10
0
40
0
0
20
10
20
0
0
0
0
60
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
0
0
10
20
0
10
20
10
0
20
10
0
10
% K
% Leu:
0
40
0
0
0
0
0
10
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
30
0
10
0
0
0
10
10
10
10
10
0
0
0
0
% N
% Pro:
0
0
40
20
10
0
0
0
0
0
0
0
0
0
50
% P
% Gln:
0
10
20
10
0
50
0
0
0
10
0
0
0
10
0
% Q
% Arg:
10
20
10
10
20
0
0
0
10
0
10
0
0
10
0
% R
% Ser:
10
0
10
10
0
0
0
30
0
20
0
0
0
0
10
% S
% Thr:
10
0
0
0
30
0
40
0
0
10
10
10
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _