KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TOE1
All Species:
11.21
Human Site:
S428
Identified Species:
27.41
UniProt:
Q96GM8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96GM8
NP_079353.3
510
56548
S428
E
V
P
G
S
Q
A
S
P
N
P
V
P
G
D
Chimpanzee
Pan troglodytes
XP_513124
565
63074
S483
E
V
P
G
S
Q
A
S
P
N
P
V
P
G
D
Rhesus Macaque
Macaca mulatta
XP_001101649
204
23337
V127
D
E
S
Q
S
Q
S
V
R
T
L
F
L
E
L
Dog
Lupus familis
XP_532601
510
56323
N428
E
A
P
E
S
Q
A
N
P
H
P
V
P
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2E2
511
56853
S429
E
L
L
V
N
Q
A
S
T
N
P
V
P
G
D
Rat
Rattus norvegicus
NP_001100150
393
44290
C316
W
C
P
L
G
P
Q
C
P
Q
S
H
D
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422434
534
59701
T430
V
F
A
R
T
V
S
T
N
H
P
D
V
P
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923913
483
54011
V396
E
K
P
K
G
K
K
V
E
G
G
T
H
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496602
490
55843
A405
D
A
F
M
T
A
F
A
V
I
Y
Q
Q
R
R
Sea Urchin
Strong. purpuratus
XP_791390
492
54720
T410
A
R
F
G
S
T
E
T
P
E
G
A
T
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.3
40
88.6
N.A.
81.5
66.4
N.A.
N.A.
55.8
N.A.
52.3
N.A.
N.A.
N.A.
28
31.1
Protein Similarity:
100
89
40
93.3
N.A.
88.4
71.3
N.A.
N.A.
73
N.A.
67.4
N.A.
N.A.
N.A.
45.6
48.4
P-Site Identity:
100
100
13.3
73.3
N.A.
66.6
20
N.A.
N.A.
6.6
N.A.
13.3
N.A.
N.A.
N.A.
0
20
P-Site Similarity:
100
100
26.6
86.6
N.A.
80
20
N.A.
N.A.
40
N.A.
20
N.A.
N.A.
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
10
0
0
10
40
10
0
0
0
10
0
0
10
% A
% Cys:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
0
0
0
0
0
0
0
0
10
10
0
50
% D
% Glu:
50
10
0
10
0
0
10
0
10
10
0
0
0
10
10
% E
% Phe:
0
10
20
0
0
0
10
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
30
20
0
0
0
0
10
20
0
0
40
0
% G
% His:
0
0
0
0
0
0
0
0
0
20
0
10
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% I
% Lys:
0
10
0
10
0
10
10
0
0
0
0
0
0
10
0
% K
% Leu:
0
10
10
10
0
0
0
0
0
0
10
0
10
0
20
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
10
10
30
0
0
0
0
0
% N
% Pro:
0
0
50
0
0
10
0
0
50
0
50
0
40
10
0
% P
% Gln:
0
0
0
10
0
50
10
0
0
10
0
10
10
0
0
% Q
% Arg:
0
10
0
10
0
0
0
0
10
0
0
0
0
20
10
% R
% Ser:
0
0
10
0
50
0
20
30
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
20
10
0
20
10
10
0
10
10
0
0
% T
% Val:
10
20
0
10
0
10
0
20
10
0
0
40
10
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _