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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TOE1
All Species:
19.7
Human Site:
S495
Identified Species:
48.15
UniProt:
Q96GM8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96GM8
NP_079353.3
510
56548
S495
A
K
S
Q
F
S
R
S
S
K
A
H
N
Q
K
Chimpanzee
Pan troglodytes
XP_513124
565
63074
S550
A
K
S
Q
F
S
R
S
S
K
A
H
N
Q
K
Rhesus Macaque
Macaca mulatta
XP_001101649
204
23337
H190
T
K
Y
A
A
E
F
H
A
R
F
V
A
S
Y
Dog
Lupus familis
XP_532601
510
56323
S495
A
K
S
Q
F
S
R
S
S
K
A
H
N
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2E2
511
56853
P496
T
K
S
Q
F
S
R
P
S
K
A
H
N
Q
K
Rat
Rattus norvegicus
NP_001100150
393
44290
E379
C
E
D
S
L
K
T
E
K
I
E
Q
K
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422434
534
59701
S519
V
K
S
S
F
S
K
S
S
A
A
H
N
Q
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923913
483
54011
S459
A
K
S
T
F
S
K
S
S
K
A
H
V
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496602
490
55843
R470
N
K
Q
R
D
Y
I
R
M
N
A
A
A
T
V
Sea Urchin
Strong. purpuratus
XP_791390
492
54720
T475
A
K
S
S
F
T
K
T
S
T
L
H
K
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.3
40
88.6
N.A.
81.5
66.4
N.A.
N.A.
55.8
N.A.
52.3
N.A.
N.A.
N.A.
28
31.1
Protein Similarity:
100
89
40
93.3
N.A.
88.4
71.3
N.A.
N.A.
73
N.A.
67.4
N.A.
N.A.
N.A.
45.6
48.4
P-Site Identity:
100
100
6.6
100
N.A.
86.6
0
N.A.
N.A.
73.3
N.A.
80
N.A.
N.A.
N.A.
13.3
46.6
P-Site Similarity:
100
100
20
100
N.A.
86.6
6.6
N.A.
N.A.
80
N.A.
86.6
N.A.
N.A.
N.A.
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
10
10
0
0
0
10
10
70
10
20
0
10
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
10
0
0
0
10
0
10
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
70
0
10
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
70
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% I
% Lys:
0
90
0
0
0
10
30
0
10
50
0
0
20
0
70
% K
% Leu:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
10
0
0
50
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
40
0
0
0
0
0
0
0
10
0
60
0
% Q
% Arg:
0
0
0
10
0
0
40
10
0
10
0
0
0
0
0
% R
% Ser:
0
0
70
30
0
60
0
50
70
0
0
0
0
10
0
% S
% Thr:
20
0
0
10
0
10
10
10
0
10
0
0
0
10
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
10
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _