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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TOE1 All Species: 3.95
Human Site: S5 Identified Species: 9.66
UniProt: Q96GM8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96GM8 NP_079353.3 510 56548 S5 _ _ _ M A A D S D D G A V S A
Chimpanzee Pan troglodytes XP_513124 565 63074 F60 T R R L Q V P F S V E W I E R
Rhesus Macaque Macaca mulatta XP_001101649 204 23337
Dog Lupus familis XP_532601 510 56323 G5 _ _ _ M A A D G D G A A A S A
Cat Felis silvestris
Mouse Mus musculus Q9D2E2 511 56853 S5 _ _ _ M A A D S D D D V P P V
Rat Rattus norvegicus NP_001100150 393 44290
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422434 534 59701 E18 V Q S D N F T E L W P S M V L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923913 483 54011 I6 _ _ M S S S M I I P V I D V Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496602 490 55843 S7 _ M S G D G D S S T T S S A G
Sea Urchin Strong. purpuratus XP_791390 492 54720 I7 _ M S L N V P I I D V H R E N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.3 40 88.6 N.A. 81.5 66.4 N.A. N.A. 55.8 N.A. 52.3 N.A. N.A. N.A. 28 31.1
Protein Similarity: 100 89 40 93.3 N.A. 88.4 71.3 N.A. N.A. 73 N.A. 67.4 N.A. N.A. N.A. 45.6 48.4
P-Site Identity: 100 0 0 66.6 N.A. 58.3 0 N.A. N.A. 0 N.A. 0 N.A. N.A. N.A. 14.2 7.1
P-Site Similarity: 100 13.3 0 66.6 N.A. 58.3 0 N.A. N.A. 13.3 N.A. 15.3 N.A. N.A. N.A. 28.5 14.2
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 30 30 0 0 0 0 10 20 10 10 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 10 0 40 0 30 30 10 0 10 0 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 10 0 0 20 0 % E
% Phe: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 10 0 10 0 10 10 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 20 20 0 0 10 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 20 0 0 0 0 10 0 0 0 0 0 10 % L
% Met: 0 20 10 30 0 0 10 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 20 0 0 10 10 0 10 10 0 % P
% Gln: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 10 10 0 0 0 0 0 0 0 0 0 10 0 10 % R
% Ser: 0 0 30 10 10 10 0 30 20 0 0 20 10 20 0 % S
% Thr: 10 0 0 0 0 0 10 0 0 10 10 0 0 0 0 % T
% Val: 10 0 0 0 0 20 0 0 0 10 20 10 10 20 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 60 40 30 0 0 0 0 0 0 0 0 0 0 0 0 % _