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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TOE1
All Species:
13.64
Human Site:
T213
Identified Species:
33.33
UniProt:
Q96GM8
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96GM8
NP_079353.3
510
56548
T213
H
L
P
E
S
L
G
T
F
T
A
D
L
C
E
Chimpanzee
Pan troglodytes
XP_513124
565
63074
T268
H
L
P
E
S
L
G
T
F
T
A
D
L
C
E
Rhesus Macaque
Macaca mulatta
XP_001101649
204
23337
Dog
Lupus familis
XP_532601
510
56323
T213
H
L
P
E
S
L
G
T
F
T
A
D
L
C
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2E2
511
56853
T213
H
L
P
E
N
L
G
T
F
T
A
D
L
C
E
Rat
Rattus norvegicus
NP_001100150
393
44290
L126
Q
V
F
N
L
T
L
L
C
M
E
E
Y
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422434
534
59701
K222
Y
L
E
Y
A
Y
K
K
C
K
R
E
N
G
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923913
483
54011
A205
G
I
Y
D
T
K
Y
A
T
E
Y
E
L
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496602
490
55843
N206
D
T
L
D
G
F
V
N
N
L
S
D
M
F
P
Sea Urchin
Strong. purpuratus
XP_791390
492
54720
M208
F
I
A
D
L
Y
E
M
Y
S
G
G
I
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.3
40
88.6
N.A.
81.5
66.4
N.A.
N.A.
55.8
N.A.
52.3
N.A.
N.A.
N.A.
28
31.1
Protein Similarity:
100
89
40
93.3
N.A.
88.4
71.3
N.A.
N.A.
73
N.A.
67.4
N.A.
N.A.
N.A.
45.6
48.4
P-Site Identity:
100
100
0
100
N.A.
93.3
0
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
100
0
100
N.A.
100
13.3
N.A.
N.A.
33.3
N.A.
33.3
N.A.
N.A.
N.A.
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
0
10
0
0
40
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
20
0
0
0
0
40
0
% C
% Asp:
10
0
0
30
0
0
0
0
0
0
0
50
0
0
10
% D
% Glu:
0
0
10
40
0
0
10
0
0
10
10
30
0
0
40
% E
% Phe:
10
0
10
0
0
10
0
0
40
0
0
0
0
10
10
% F
% Gly:
10
0
0
0
10
0
40
0
0
0
10
10
0
10
0
% G
% His:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
20
0
0
0
0
0
0
0
0
0
0
10
10
10
% I
% Lys:
0
0
0
0
0
10
10
10
0
10
0
0
0
0
10
% K
% Leu:
0
50
10
0
20
40
10
10
0
10
0
0
50
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
10
0
0
10
0
0
% M
% Asn:
0
0
0
10
10
0
0
10
10
0
0
0
10
0
0
% N
% Pro:
0
0
40
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% R
% Ser:
0
0
0
0
30
0
0
0
0
10
10
0
0
0
0
% S
% Thr:
0
10
0
0
10
10
0
40
10
40
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
10
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
10
0
20
10
0
10
0
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _