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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TOE1
All Species:
20.61
Human Site:
Y477
Identified Species:
50.37
UniProt:
Q96GM8
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96GM8
NP_079353.3
510
56548
Y477
P
E
C
H
N
K
V
Y
L
S
G
K
A
V
P
Chimpanzee
Pan troglodytes
XP_513124
565
63074
Y532
P
E
C
H
N
K
V
Y
L
S
G
K
A
V
P
Rhesus Macaque
Macaca mulatta
XP_001101649
204
23337
L172
L
G
T
F
T
A
D
L
C
E
M
F
P
A
G
Dog
Lupus familis
XP_532601
510
56323
Y477
P
E
C
H
N
K
V
Y
L
S
G
K
A
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2E2
511
56853
Y478
P
E
C
H
N
K
V
Y
L
S
G
K
T
V
P
Rat
Rattus norvegicus
NP_001100150
393
44290
E361
P
E
T
Q
T
L
E
E
A
E
D
G
P
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422434
534
59701
Y501
P
D
C
H
N
K
L
Y
L
S
G
K
S
V
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923913
483
54011
F441
S
T
C
L
N
K
L
F
L
S
G
K
S
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496602
490
55843
I452
P
V
P
Q
S
E
Q
I
D
A
H
L
E
A
M
Sea Urchin
Strong. purpuratus
XP_791390
492
54720
Y457
G
H
L
T
N
K
L
Y
L
S
G
K
D
Y
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.3
40
88.6
N.A.
81.5
66.4
N.A.
N.A.
55.8
N.A.
52.3
N.A.
N.A.
N.A.
28
31.1
Protein Similarity:
100
89
40
93.3
N.A.
88.4
71.3
N.A.
N.A.
73
N.A.
67.4
N.A.
N.A.
N.A.
45.6
48.4
P-Site Identity:
100
100
0
100
N.A.
93.3
13.3
N.A.
N.A.
80
N.A.
60
N.A.
N.A.
N.A.
6.6
53.3
P-Site Similarity:
100
100
0
100
N.A.
93.3
13.3
N.A.
N.A.
100
N.A.
80
N.A.
N.A.
N.A.
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
10
10
0
0
30
20
0
% A
% Cys:
0
0
60
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
10
0
10
0
10
0
10
0
0
% D
% Glu:
0
50
0
0
0
10
10
10
0
20
0
0
10
0
0
% E
% Phe:
0
0
0
10
0
0
0
10
0
0
0
10
0
0
0
% F
% Gly:
10
10
0
0
0
0
0
0
0
0
70
10
0
0
10
% G
% His:
0
10
0
50
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
70
0
0
0
0
0
70
0
0
0
% K
% Leu:
10
0
10
10
0
10
30
10
70
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% M
% Asn:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
70
0
10
0
0
0
0
0
0
0
0
0
20
10
70
% P
% Gln:
0
0
0
20
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
10
0
0
0
0
70
0
0
20
0
0
% S
% Thr:
0
10
20
10
20
0
0
0
0
0
0
0
10
0
10
% T
% Val:
0
10
0
0
0
0
40
0
0
0
0
0
0
60
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _