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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZDHHC12 All Species: 12.12
Human Site: S263 Identified Species: 29.63
UniProt: Q96GR4 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96GR4 NP_116188.2 267 30813 S263 A E E E E E G S S P A V _ _ _
Chimpanzee Pan troglodytes XP_520297 267 30819 S263 A E E E E E G S S P A V _ _ _
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_861511 269 30774 E263 A E G E E E E E G G S Q A V _
Cat Felis silvestris
Mouse Mus musculus Q8VC90 267 30689 S263 A E E E E E G S S Q V V _ _ _
Rat Rattus norvegicus Q6DGF5 267 31011 S263 A E E E E E G S S Q V V _ _ _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506533 232 26485
Chicken Gallus gallus XP_415490 261 30274 H255 A W E K I Y F H R N N E P V _
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_697586 270 31222 V261 E P V V W E H V Y F K Q G N D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394622 606 67936 G575 F C N L S F C G V K A K P S S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795371 320 37729 L316 M L V R Y S D L E N A S _ _ _
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 N.A. 94.8 N.A. 87.2 90.6 N.A. 60.2 53.1 N.A. 55.5 N.A. N.A. 20.1 N.A. 35
Protein Similarity: 100 98.5 N.A. 95.1 N.A. 90.6 92.5 N.A. 68.5 71.1 N.A. 71.1 N.A. N.A. 27.2 N.A. 49
P-Site Identity: 100 100 N.A. 35.7 N.A. 83.3 83.3 N.A. 0 14.2 N.A. 6.6 N.A. N.A. 6.6 N.A. 8.3
P-Site Similarity: 100 100 N.A. 42.8 N.A. 83.3 83.3 N.A. 0 21.4 N.A. 13.3 N.A. N.A. 6.6 N.A. 8.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 60 0 0 0 0 0 0 0 0 0 40 0 10 0 0 % A
% Cys: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % D
% Glu: 10 50 50 50 50 60 10 10 10 0 0 10 0 0 0 % E
% Phe: 10 0 0 0 0 10 10 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 40 10 10 10 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 10 10 10 0 0 0 % K
% Leu: 0 10 0 10 0 0 0 10 0 0 0 0 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 20 10 0 0 10 0 % N
% Pro: 0 10 0 0 0 0 0 0 0 20 0 0 20 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 20 0 20 0 0 0 % Q
% Arg: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 10 10 0 40 40 0 10 10 0 10 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 20 10 0 0 0 10 10 0 20 40 0 20 0 % V
% Trp: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 10 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 50 50 70 % _