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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MASTL All Species: 12.42
Human Site: T381 Identified Species: 34.17
UniProt: Q96GX5 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96GX5 NP_116233.2 879 97319 T381 N S S A L P T T G R S C V N L
Chimpanzee Pan troglodytes XP_001160397 957 105363 T459 N S S A L P T T G R S C V N L
Rhesus Macaque Macaca mulatta XP_001104617 880 97512 T382 N S S A L P T T G R S C V N L
Dog Lupus familis XP_848866 880 97694 A381 H N S S I I P A T G S S C V N
Cat Felis silvestris
Mouse Mus musculus Q8C0P0 865 95942 T379 A A G S N Q V T L P R K C F R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506948 886 97580 S380 S E L C D A G S A S L I A S E
Chicken Gallus gallus XP_418589 889 98887 E376 S R Q K L G T E R S E I T D T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001003609 860 95711 I379 Q V N N S R N I K P D L S A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394554 715 79287 T250 T P S L C T R T P G Q L L S L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.2 96.5 83 N.A. 74.4 N.A. N.A. 65 60.2 N.A. 50 N.A. N.A. 24.5 N.A. N.A.
Protein Similarity: 100 91.5 98.1 89.3 N.A. 84.6 N.A. N.A. 75.4 73 N.A. 65.1 N.A. N.A. 40.9 N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. 6.6 N.A. N.A. 0 13.3 N.A. 0 N.A. N.A. 20 N.A. N.A.
P-Site Similarity: 100 100 100 40 N.A. 20 N.A. N.A. 20 26.6 N.A. 6.6 N.A. N.A. 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 0 34 0 12 0 12 12 0 0 0 12 12 0 % A
% Cys: 0 0 0 12 12 0 0 0 0 0 0 34 23 0 0 % C
% Asp: 0 0 0 0 12 0 0 0 0 0 12 0 0 12 0 % D
% Glu: 0 12 0 0 0 0 0 12 0 0 12 0 0 0 12 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % F
% Gly: 0 0 12 0 0 12 12 0 34 23 0 0 0 0 0 % G
% His: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 12 12 0 12 0 0 0 23 0 0 0 % I
% Lys: 0 0 0 12 0 0 0 0 12 0 0 12 0 0 12 % K
% Leu: 0 0 12 12 45 0 0 0 12 0 12 23 12 0 45 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 34 12 12 12 12 0 12 0 0 0 0 0 0 34 12 % N
% Pro: 0 12 0 0 0 34 12 0 12 23 0 0 0 0 0 % P
% Gln: 12 0 12 0 0 12 0 0 0 0 12 0 0 0 0 % Q
% Arg: 0 12 0 0 0 12 12 0 12 34 12 0 0 0 12 % R
% Ser: 23 34 56 23 12 0 0 12 0 23 45 12 12 23 0 % S
% Thr: 12 0 0 0 0 12 45 56 12 0 0 0 12 0 12 % T
% Val: 0 12 0 0 0 0 12 0 0 0 0 0 34 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _