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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPN
All Species:
17.27
Human Site:
S218
Identified Species:
42.22
UniProt:
Q96H22
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96H22
NP_001094094.1
339
39541
S218
Q
T
F
E
T
H
N
S
T
T
P
L
Q
E
R
Chimpanzee
Pan troglodytes
XP_511126
339
39532
S218
Q
T
F
E
T
H
N
S
T
T
P
L
Q
E
R
Rhesus Macaque
Macaca mulatta
XP_001111366
339
39508
S218
Q
T
F
E
T
H
N
S
A
T
P
L
Q
E
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZW2
337
39222
S218
Q
T
C
E
N
Y
S
S
T
T
S
L
Q
E
A
Rat
Rattus norvegicus
Q5U2W4
340
39441
S219
Q
T
F
E
N
Y
N
S
T
A
S
W
R
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508634
381
44302
P218
Q
A
I
Q
V
H
Y
P
R
P
L
Q
E
R
N
Chicken
Gallus gallus
Q1T765
344
40326
P217
Q
N
F
Q
T
N
Y
P
L
Q
E
R
N
V
L
Frog
Xenopus laevis
Q5XH29
348
39710
S216
Q
P
F
S
S
H
H
S
I
P
H
E
K
A
L
Zebra Danio
Brachydanio rerio
NP_001002341
345
39262
K217
V
F
P
S
A
Q
S
K
I
Q
Q
E
R
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789578
334
38496
N216
S
L
A
D
L
T
L
N
P
A
S
Q
G
W
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.7
N.A.
N.A.
72.8
71.4
N.A.
55.3
59
50.2
31.5
N.A.
N.A.
N.A.
N.A.
26.2
Protein Similarity:
100
99.4
98.2
N.A.
N.A.
87.3
85.5
N.A.
70.3
75.5
69.8
56.2
N.A.
N.A.
N.A.
N.A.
47.2
P-Site Identity:
100
100
93.3
N.A.
N.A.
60
53.3
N.A.
13.3
20
26.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
N.A.
N.A.
73.3
66.6
N.A.
26.6
33.3
46.6
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
10
0
0
0
10
20
0
0
0
10
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
50
0
0
0
0
0
0
10
20
10
50
0
% E
% Phe:
0
10
60
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% G
% His:
0
0
0
0
0
50
10
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
20
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% K
% Leu:
0
10
0
0
10
0
10
0
10
0
10
40
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
20
10
40
10
0
0
0
0
10
0
10
% N
% Pro:
0
10
10
0
0
0
0
20
10
20
30
0
0
0
0
% P
% Gln:
80
0
0
20
0
10
0
0
0
20
10
20
40
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
10
20
10
30
% R
% Ser:
10
0
0
20
10
0
20
60
0
0
30
0
0
0
10
% S
% Thr:
0
50
0
0
40
10
0
0
40
40
0
0
0
0
0
% T
% Val:
10
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% W
% Tyr:
0
0
0
0
0
20
20
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _