Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CENPN All Species: 8.79
Human Site: S282 Identified Species: 21.48
UniProt: Q96H22 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96H22 NP_001094094.1 339 39541 S282 F K S G L N G S I L A E R E E
Chimpanzee Pan troglodytes XP_511126 339 39532 S282 F K S G L N G S I L A E R E E
Rhesus Macaque Macaca mulatta XP_001111366 339 39508 S282 F K S D L N G S I L A E R E K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9CZW2 337 39222 G280 F K S N I G G G L L A D R K E
Rat Rattus norvegicus Q5U2W4 340 39441 G283 F K S D V G G G I L A D R K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508634 381 44302 G281 F R R D T G M G I L G A K E E
Chicken Gallus gallus Q1T765 344 40326 L279 S D P K W D V L E K K E P F R
Frog Xenopus laevis Q5XH29 348 39710 N279 A E S I M D G N L T A V N E P
Zebra Danio Brachydanio rerio NP_001002341 345 39262 V287 R E E F F R G V V R F S S S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789578 334 38496 N278 L D S S F G T N K Q P K L E R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 96.7 N.A. N.A. 72.8 71.4 N.A. 55.3 59 50.2 31.5 N.A. N.A. N.A. N.A. 26.2
Protein Similarity: 100 99.4 98.2 N.A. N.A. 87.3 85.5 N.A. 70.3 75.5 69.8 56.2 N.A. N.A. N.A. N.A. 47.2
P-Site Identity: 100 100 86.6 N.A. N.A. 53.3 60 N.A. 33.3 6.6 26.6 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 93.3 N.A. N.A. 80 80 N.A. 46.6 13.3 60 20 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 0 60 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 20 0 30 0 20 0 0 0 0 0 20 0 0 0 % D
% Glu: 0 20 10 0 0 0 0 0 10 0 0 40 0 60 50 % E
% Phe: 60 0 0 10 20 0 0 0 0 0 10 0 0 10 0 % F
% Gly: 0 0 0 20 0 40 70 30 0 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 10 0 0 0 50 0 0 0 0 0 0 % I
% Lys: 0 50 0 10 0 0 0 0 10 10 10 10 10 20 10 % K
% Leu: 10 0 0 0 30 0 0 10 20 60 0 0 10 0 0 % L
% Met: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 30 0 20 0 0 0 0 10 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 0 0 10 0 10 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 10 10 10 0 0 10 0 0 0 10 0 0 50 0 20 % R
% Ser: 10 0 70 10 0 0 0 30 0 0 0 10 10 10 10 % S
% Thr: 0 0 0 0 10 0 10 0 0 10 0 0 0 0 0 % T
% Val: 0 0 0 0 10 0 10 10 10 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _