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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPN
All Species:
20.91
Human Site:
T252
Identified Species:
51.11
UniProt:
Q96H22
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96H22
NP_001094094.1
339
39541
T252
K
E
R
V
Q
R
I
T
Q
E
T
F
G
D
Y
Chimpanzee
Pan troglodytes
XP_511126
339
39532
T252
K
E
R
V
Q
R
I
T
Q
E
T
F
G
D
Y
Rhesus Macaque
Macaca mulatta
XP_001111366
339
39508
T252
K
E
R
V
Q
R
I
T
Q
E
T
F
G
D
Y
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZW2
337
39222
T250
K
V
R
V
H
R
V
T
Q
E
T
F
G
T
Y
Rat
Rattus norvegicus
Q5U2W4
340
39441
T253
K
V
R
I
H
R
A
T
Q
E
A
F
G
A
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508634
381
44302
T251
K
E
K
I
L
R
V
T
K
E
T
F
G
D
G
Chicken
Gallus gallus
Q1T765
344
40326
E249
R
I
Y
R
L
N
Q
E
S
F
G
N
G
P
Q
Frog
Xenopus laevis
Q5XH29
348
39710
E249
R
V
S
H
L
T
R
E
T
F
G
E
G
P
L
Zebra Danio
Brachydanio rerio
NP_001002341
345
39262
K257
F
G
H
G
P
T
P
K
L
E
T
A
V
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789578
334
38496
S248
T
R
K
R
R
G
D
S
L
D
L
E
D
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.7
N.A.
N.A.
72.8
71.4
N.A.
55.3
59
50.2
31.5
N.A.
N.A.
N.A.
N.A.
26.2
Protein Similarity:
100
99.4
98.2
N.A.
N.A.
87.3
85.5
N.A.
70.3
75.5
69.8
56.2
N.A.
N.A.
N.A.
N.A.
47.2
P-Site Identity:
100
100
100
N.A.
N.A.
73.3
60
N.A.
60
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
N.A.
N.A.
80
66.6
N.A.
86.6
13.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
10
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
10
0
0
10
40
0
% D
% Glu:
0
40
0
0
0
0
0
20
0
70
0
20
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
20
0
60
0
0
0
% F
% Gly:
0
10
0
10
0
10
0
0
0
0
20
0
80
0
10
% G
% His:
0
0
10
10
20
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
20
0
0
30
0
0
0
0
0
0
0
0
% I
% Lys:
60
0
20
0
0
0
0
10
10
0
0
0
0
10
10
% K
% Leu:
0
0
0
0
30
0
0
0
20
0
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
10
0
10
0
0
0
0
0
0
20
0
% P
% Gln:
0
0
0
0
30
0
10
0
50
0
0
0
0
0
10
% Q
% Arg:
20
10
50
20
10
60
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
10
% S
% Thr:
10
0
0
0
0
20
0
60
10
0
60
0
0
10
0
% T
% Val:
0
30
0
40
0
0
20
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _