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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CENPN All Species: 22.42
Human Site: Y269 Identified Species: 54.81
UniProt: Q96H22 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96H22 NP_001094094.1 339 39541 Y269 P Q L E F A Q Y K L E T K F K
Chimpanzee Pan troglodytes XP_511126 339 39532 Y269 P Q L E F A Q Y K L E T K F K
Rhesus Macaque Macaca mulatta XP_001111366 339 39508 Y269 P Q L E F A Q Y K L E T K F K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9CZW2 337 39222 Y267 P Q L E F A Q Y K L E T K F K
Rat Rattus norvegicus Q5U2W4 340 39441 Y270 P Q L E F A Q Y K L E T K F K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508634 381 44302 Y268 P K L E F A Q Y K L E T V F R
Chicken Gallus gallus Q1T765 344 40326 L266 L D F A Q Y K L E T M F K S D
Frog Xenopus laevis Q5XH29 348 39710 L266 L E L A S Y K L E T M F R A E
Zebra Danio Brachydanio rerio NP_001002341 345 39262 N274 T R Y R G N G N L T V S D R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789578 334 38496 E265 S E N V E D E E K C Q K D L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 96.7 N.A. N.A. 72.8 71.4 N.A. 55.3 59 50.2 31.5 N.A. N.A. N.A. N.A. 26.2
Protein Similarity: 100 99.4 98.2 N.A. N.A. 87.3 85.5 N.A. 70.3 75.5 69.8 56.2 N.A. N.A. N.A. N.A. 47.2
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. 80 6.6 6.6 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 93.3 20 40 20 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 20 0 60 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 10 0 0 0 0 0 0 20 0 20 % D
% Glu: 0 20 0 60 10 0 10 10 20 0 60 0 0 0 20 % E
% Phe: 0 0 10 0 60 0 0 0 0 0 0 20 0 60 0 % F
% Gly: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 20 0 70 0 0 10 60 0 50 % K
% Leu: 20 0 70 0 0 0 0 20 10 60 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % M
% Asn: 0 0 10 0 0 10 0 10 0 0 0 0 0 0 0 % N
% Pro: 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 50 0 0 10 0 60 0 0 0 10 0 0 0 0 % Q
% Arg: 0 10 0 10 0 0 0 0 0 0 0 0 10 10 10 % R
% Ser: 10 0 0 0 10 0 0 0 0 0 0 10 0 10 0 % S
% Thr: 10 0 0 0 0 0 0 0 0 30 0 60 0 0 0 % T
% Val: 0 0 0 10 0 0 0 0 0 0 10 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 20 0 60 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _