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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDYHV1 All Species: 38.18
Human Site: T168 Identified Species: 60
UniProt: Q96HA8 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HA8 NP_060494.1 205 23680 T168 P P Y P C I E T G D S K M N L
Chimpanzee Pan troglodytes XP_519939 205 23648 T168 P P Y P C I E T G D S K M N L
Rhesus Macaque Macaca mulatta XP_001100514 205 23602 T168 P P Y P C I E T G D S K M N L
Dog Lupus familis XP_851629 330 36545 T293 P S Y P C I E T G D S K M N L
Cat Felis silvestris
Mouse Mus musculus Q80WB5 209 24318 T170 P E Y P C I E T G D S K M N L
Rat Rattus norvegicus Q5BJV9 207 24107 T170 P E Y P C I E T G D S K M N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511906 205 23817 T169 P L Y P C I E T A D S K M N L
Chicken Gallus gallus XP_418452 211 24566 T166 P S Y P C I E T A D S K M N L
Frog Xenopus laevis Q5PPU8 204 23368 S164 P P Y P C I Q S A E S T M N L
Zebra Danio Brachydanio rerio Q1LWX3 202 23527 C164 M P P P A Y P C L E T P E S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K2Y9 205 23988 S161 P S Y P P I L S N S N M H C L
Honey Bee Apis mellifera XP_001121338 223 25930 T171 P D Y P P I S T S T C K D N L
Nematode Worm Caenorhab. elegans Q21775 184 21574 L148 K P P P E W P L I N S H K P S
Sea Urchin Strong. purpuratus XP_780924 203 23344 A165 P S H P C I V A K D G T T M N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22944 221 24954 A168 P P Y E P I V A Q D G I L H N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 97 58.7 N.A. 82.7 85.5 N.A. 70.7 64.9 59 63.4 N.A. 46.8 40.3 36.5 40.4
Protein Similarity: 100 100 98.5 60.9 N.A. 88 89.8 N.A. 80.9 81 74.1 75.1 N.A. 61.9 58.2 53.1 57.5
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 86.6 86.6 66.6 13.3 N.A. 33.3 53.3 20 33.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 86.6 86.6 86.6 33.3 N.A. 46.6 53.3 26.6 40
Percent
Protein Identity: N.A. N.A. N.A. 31.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 51.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 0 0 14 20 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 67 0 0 7 0 0 7 0 0 7 0 % C
% Asp: 0 7 0 0 0 0 0 0 0 67 0 0 7 0 0 % D
% Glu: 0 14 0 7 7 0 54 0 0 14 0 0 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 40 0 14 0 0 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 7 7 7 0 % H
% Ile: 0 0 0 0 0 87 0 0 7 0 0 7 0 0 0 % I
% Lys: 7 0 0 0 0 0 0 0 7 0 0 60 7 0 7 % K
% Leu: 0 7 0 0 0 0 7 7 7 0 0 0 7 0 74 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 7 60 7 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 7 7 0 0 67 14 % N
% Pro: 87 47 14 94 20 0 14 0 0 0 0 7 0 7 0 % P
% Gln: 0 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 27 0 0 0 0 7 14 7 7 67 0 0 7 7 % S
% Thr: 0 0 0 0 0 0 0 60 0 7 7 14 7 0 0 % T
% Val: 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 80 0 0 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _