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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDYHV1
All Species:
30.91
Human Site:
Y45
Identified Species:
48.57
UniProt:
Q96HA8
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HA8
NP_060494.1
205
23680
Y45
Y
I
K
N
H
D
Q
Y
P
L
E
E
C
Y
A
Chimpanzee
Pan troglodytes
XP_519939
205
23648
Y45
Y
I
R
N
H
D
Q
Y
P
L
E
E
C
Y
A
Rhesus Macaque
Macaca mulatta
XP_001100514
205
23602
Y45
Y
I
K
N
H
D
Q
Y
P
L
Q
E
C
Y
A
Dog
Lupus familis
XP_851629
330
36545
Y170
Y
I
K
N
H
D
Q
Y
P
L
E
E
C
Y
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80WB5
209
24318
Y47
Y
I
K
T
H
N
Q
Y
L
L
E
E
C
Y
A
Rat
Rattus norvegicus
Q5BJV9
207
24107
Y47
Y
I
K
T
H
N
Q
Y
L
L
E
E
C
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511906
205
23817
Y46
Y
I
Q
N
R
N
R
Y
P
L
E
E
F
Y
A
Chicken
Gallus gallus
XP_418452
211
24566
Y43
Y
I
R
S
Q
D
R
Y
P
L
E
E
F
Y
A
Frog
Xenopus laevis
Q5PPU8
204
23368
L42
I
R
D
H
R
P
C
L
L
E
Q
F
S
A
V
Zebra Danio
Brachydanio rerio
Q1LWX3
202
23527
C44
Y
I
K
N
Q
R
H
C
P
L
E
E
V
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K2Y9
205
23988
F46
L
S
K
C
Y
A
V
F
V
S
N
E
G
R
T
Honey Bee
Apis mellifera
XP_001121338
223
25930
S48
D
V
A
T
R
H
G
S
E
L
Q
H
C
Y
V
Nematode Worm
Caenorhab. elegans
Q21775
184
21574
N38
I
F
A
I
I
I
S
N
D
C
K
M
I
P
L
Sea Urchin
Strong. purpuratus
XP_780924
203
23344
E42
V
Q
K
N
F
P
N
E
L
S
R
A
Y
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22944
221
24954
A42
C
E
N
G
V
A
E
A
T
C
S
D
L
F
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
97
58.7
N.A.
82.7
85.5
N.A.
70.7
64.9
59
63.4
N.A.
46.8
40.3
36.5
40.4
Protein Similarity:
100
100
98.5
60.9
N.A.
88
89.8
N.A.
80.9
81
74.1
75.1
N.A.
61.9
58.2
53.1
57.5
P-Site Identity:
100
93.3
93.3
100
N.A.
80
80
N.A.
66.6
66.6
0
66.6
N.A.
13.3
20
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
86.6
86.6
13.3
66.6
N.A.
26.6
33.3
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
0
0
14
0
7
0
0
0
7
0
14
60
% A
% Cys:
7
0
0
7
0
0
7
7
0
14
0
0
47
0
0
% C
% Asp:
7
0
7
0
0
34
0
0
7
0
0
7
0
0
0
% D
% Glu:
0
7
0
0
0
0
7
7
7
7
54
67
0
0
0
% E
% Phe:
0
7
0
0
7
0
0
7
0
0
0
7
14
7
0
% F
% Gly:
0
0
0
7
0
0
7
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
7
40
7
7
0
0
0
0
7
0
0
0
% H
% Ile:
14
60
0
7
7
7
0
0
0
0
0
0
7
0
0
% I
% Lys:
0
0
54
0
0
0
0
0
0
0
7
0
0
0
0
% K
% Leu:
7
0
0
0
0
0
0
7
27
67
0
0
7
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
7
47
0
20
7
7
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
14
0
0
47
0
0
0
0
7
0
% P
% Gln:
0
7
7
0
14
0
40
0
0
0
20
0
0
0
0
% Q
% Arg:
0
7
14
0
20
7
14
0
0
0
7
0
0
7
0
% R
% Ser:
0
7
0
7
0
0
7
7
0
14
7
0
7
0
0
% S
% Thr:
0
0
0
20
0
0
0
0
7
0
0
0
0
0
7
% T
% Val:
7
7
0
0
7
0
7
0
7
0
0
0
7
0
27
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
60
0
0
0
7
0
0
54
0
0
0
0
7
67
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _