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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDYHV1 All Species: 36.97
Human Site: Y51 Identified Species: 58.1
UniProt: Q96HA8 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HA8 NP_060494.1 205 23680 Y51 Q Y P L E E C Y A V F I S N E
Chimpanzee Pan troglodytes XP_519939 205 23648 Y51 Q Y P L E E C Y A V F I S N E
Rhesus Macaque Macaca mulatta XP_001100514 205 23602 Y51 Q Y P L Q E C Y A V F I S N E
Dog Lupus familis XP_851629 330 36545 Y176 Q Y P L E E C Y A V F I S N E
Cat Felis silvestris
Mouse Mus musculus Q80WB5 209 24318 Y53 Q Y L L E E C Y A V F I S N E
Rat Rattus norvegicus Q5BJV9 207 24107 Y53 Q Y L L E E C Y A V F I S N E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511906 205 23817 Y52 R Y P L E E F Y A V F I S N E
Chicken Gallus gallus XP_418452 211 24566 Y49 R Y P L E E F Y A V F I S N D
Frog Xenopus laevis Q5PPU8 204 23368 A48 C L L E Q F S A V F I S N E N
Zebra Danio Brachydanio rerio Q1LWX3 202 23527 Y50 H C P L E E V Y A V F I S N E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K2Y9 205 23988 R52 V F V S N E G R T V P L W R Q
Honey Bee Apis mellifera XP_001121338 223 25930 Y54 G S E L Q H C Y V V F V S N S
Nematode Worm Caenorhab. elegans Q21775 184 21574 P44 S N D C K M I P L W K Q K A A
Sea Urchin Strong. purpuratus XP_780924 203 23344 A48 N E L S R A Y A V F I S N D E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22944 221 24954 F48 E A T C S D L F V V F I S N E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 97 58.7 N.A. 82.7 85.5 N.A. 70.7 64.9 59 63.4 N.A. 46.8 40.3 36.5 40.4
Protein Similarity: 100 100 98.5 60.9 N.A. 88 89.8 N.A. 80.9 81 74.1 75.1 N.A. 61.9 58.2 53.1 57.5
P-Site Identity: 100 100 93.3 100 N.A. 93.3 93.3 N.A. 86.6 80 0 80 N.A. 13.3 46.6 0 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 93.3 13.3 80 N.A. 33.3 60 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. 31.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 51.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 7 0 14 60 0 0 0 0 7 7 % A
% Cys: 7 7 0 14 0 0 47 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 7 0 0 0 0 0 0 0 7 7 % D
% Glu: 7 7 7 7 54 67 0 0 0 0 0 0 0 7 67 % E
% Phe: 0 7 0 0 0 7 14 7 0 14 74 0 0 0 0 % F
% Gly: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % G
% His: 7 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 7 0 0 0 14 67 0 0 0 % I
% Lys: 0 0 0 0 7 0 0 0 0 0 7 0 7 0 0 % K
% Leu: 0 7 27 67 0 0 7 0 7 0 0 7 0 0 0 % L
% Met: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 7 0 0 7 0 0 0 0 0 0 0 14 74 7 % N
% Pro: 0 0 47 0 0 0 0 7 0 0 7 0 0 0 0 % P
% Gln: 40 0 0 0 20 0 0 0 0 0 0 7 0 0 7 % Q
% Arg: 14 0 0 0 7 0 0 7 0 0 0 0 0 7 0 % R
% Ser: 7 7 0 14 7 0 7 0 0 0 0 14 74 0 7 % S
% Thr: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % T
% Val: 7 0 7 0 0 0 7 0 27 80 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 7 0 0 % W
% Tyr: 0 54 0 0 0 0 7 67 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _