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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACY3
All Species:
19.39
Human Site:
T74
Identified Species:
47.41
UniProt:
Q96HD9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HD9
NP_542389.1
319
35241
T74
H
D
L
N
R
T
F
T
S
S
F
L
N
S
R
Chimpanzee
Pan troglodytes
XP_508599
319
35227
T74
H
D
L
N
R
T
F
T
S
S
F
L
N
S
R
Rhesus Macaque
Macaca mulatta
XP_001104661
319
35242
T74
H
D
L
N
R
A
F
T
S
S
F
L
N
S
R
Dog
Lupus familis
XP_854515
313
35736
D74
C
D
L
N
R
V
F
D
P
E
N
L
G
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91XE4
318
35268
T74
R
D
L
N
R
S
C
T
L
T
F
L
G
S
T
Rat
Rattus norvegicus
Q5M876
319
35401
T74
R
D
L
N
R
T
F
T
L
T
F
L
G
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508678
315
35756
D75
C
D
L
N
R
V
F
D
L
E
N
L
C
K
K
Chicken
Gallus gallus
XP_415853
345
39116
D101
C
D
L
N
R
V
F
D
P
D
N
L
G
Q
T
Frog
Xenopus laevis
A0JMS7
305
34292
S77
E
L
L
S
A
S
A
S
E
S
D
S
Y
E
V
Zebra Danio
Brachydanio rerio
A8KB34
315
35516
T76
T
D
L
N
R
A
F
T
P
E
N
L
S
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
95.3
43.5
N.A.
68.6
68.6
N.A.
43.2
41.4
49.2
43.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
97.4
60.5
N.A.
81.5
82.7
N.A.
61.4
56.2
66.4
60.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
40
N.A.
53.3
66.6
N.A.
40
40
13.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
46.6
N.A.
66.6
73.3
N.A.
46.6
40
33.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
20
10
0
0
0
0
0
0
10
0
% A
% Cys:
30
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% C
% Asp:
0
90
0
0
0
0
0
30
0
10
10
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
10
30
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
80
0
0
0
50
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
0
% G
% His:
30
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
20
% K
% Leu:
0
10
100
0
0
0
0
0
30
0
0
90
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
90
0
0
0
0
0
0
40
0
30
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
20
0
0
0
90
0
0
0
0
0
0
0
0
0
30
% R
% Ser:
0
0
0
10
0
20
0
10
30
40
0
10
10
50
10
% S
% Thr:
10
0
0
0
0
30
0
60
0
20
0
0
0
0
30
% T
% Val:
0
0
0
0
0
30
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _