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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACY3 All Species: 9.09
Human Site: Y147 Identified Species: 22.22
UniProt: Q96HD9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HD9 NP_542389.1 319 35241 Y147 C R H L Q L Q Y P E L S C Q V
Chimpanzee Pan troglodytes XP_508599 319 35227 Y147 C R H L Q L Q Y P E L S C Q V
Rhesus Macaque Macaca mulatta XP_001104661 319 35242 Y147 C R H L Q L Q Y P E L S C Q V
Dog Lupus familis XP_854515 313 35736 L147 F H Y I K N S L A P L P C Y V
Cat Felis silvestris
Mouse Mus musculus Q91XE4 318 35268 N146 C H Y L Q R Q N P G M P C R L
Rat Rattus norvegicus Q5M876 319 35401 N147 C H Y L Q L Q N P G L P C R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508678 315 35756 L148 V H Y I Q N S L A P L P C Y V
Chicken Gallus gallus XP_415853 345 39116 L174 C H Y I K N A L A P E R V P V
Frog Xenopus laevis A0JMS7 305 34292 L149 S F P C H I L L I D I P E Q G
Zebra Danio Brachydanio rerio A8KB34 315 35516 M149 V H Y I K K A M A P H T C S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 95.3 43.5 N.A. 68.6 68.6 N.A. 43.2 41.4 49.2 43.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 97.4 60.5 N.A. 81.5 82.7 N.A. 61.4 56.2 66.4 60.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 20 N.A. 40 53.3 N.A. 26.6 13.3 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 40 N.A. 66.6 73.3 N.A. 40 33.3 26.6 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 20 0 40 0 0 0 0 0 0 % A
% Cys: 60 0 0 10 0 0 0 0 0 0 0 0 80 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 30 10 0 10 0 0 % E
% Phe: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 10 % G
% His: 0 60 30 0 10 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 40 0 10 0 0 10 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 30 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 50 0 40 10 40 0 0 60 0 0 0 20 % L
% Met: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 30 0 20 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 50 40 0 50 0 10 0 % P
% Gln: 0 0 0 0 60 0 50 0 0 0 0 0 0 40 0 % Q
% Arg: 0 30 0 0 0 10 0 0 0 0 0 10 0 20 0 % R
% Ser: 10 0 0 0 0 0 20 0 0 0 0 30 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % T
% Val: 20 0 0 0 0 0 0 0 0 0 0 0 10 0 70 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 60 0 0 0 0 30 0 0 0 0 0 20 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _