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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERO1L All Species: 33.94
Human Site: S106 Identified Species: 46.67
UniProt: Q96HE7 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HE7 NP_055399.1 468 54393 S106 C A V K P C Q S D E V P D G I
Chimpanzee Pan troglodytes XP_509950 468 54427 S106 C A V K P C Q S D E V P D G I
Rhesus Macaque Macaca mulatta XP_001103965 468 54383 S106 C A V K P C Q S D E V P D G I
Dog Lupus familis XP_547813 468 54343 S106 C A V K P C Q S D E V P D G I
Cat Felis silvestris
Mouse Mus musculus Q8R180 464 54066 S106 C A V K P C H S D E V P D G I
Rat Rattus norvegicus Q8R4A1 464 54000 S106 C A V K P C H S D E V P D G I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515503 465 53870 S103 C A V K P C Q S N E V P D G I
Chicken Gallus gallus XP_421473 463 52908 S104 C A V K P C P S D E V P D G I
Frog Xenopus laevis Q6DD71 465 53720 S102 C A V N P C S S D E V P G F K
Zebra Danio Brachydanio rerio Q7T3D1 489 56571 P98 C A V K P C S P D E V P E G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3A6 483 55641 E115 C Q V E N C E E Q A I P Q G I
Honey Bee Apis mellifera XP_623933 471 55049 D110 C H V Q P C Q D E D I P D G L
Nematode Worm Caenorhab. elegans Q7YTU4 478 55136 D100 C G I A F C D D E V P A G L R
Sea Urchin Strong. purpuratus XP_796844 897 101920 P523 C H V C P C S P D D L P C G L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C7S7 469 53812 E129 C S V C E C P E N E F P E P F
Baker's Yeast Sacchar. cerevisiae Q03103 563 65014 E111 A C S V D V V E D W D T L P E
Red Bread Mold Neurospora crassa Q7SEY9 668 75589 L99 I A C A V E T L D N E E D I P
Conservation
Percent
Protein Identity: 100 99.5 98.7 96.3 N.A. 91.8 91.4 N.A. 84.6 77.7 70.9 62.1 N.A. 46.1 48.4 41.4 29.3
Protein Similarity: 100 99.5 99.3 97.8 N.A. 95.9 95.7 N.A. 90.1 85.4 83.9 75.4 N.A. 64.1 65.6 60.8 37.6
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 93.3 66.6 73.3 N.A. 40 53.3 13.3 46.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 93.3 66.6 86.6 N.A. 60 86.6 26.6 66.6
Percent
Protein Identity: N.A. N.A. N.A. 37.9 22.5 22.1
Protein Similarity: N.A. N.A. N.A. 55.6 41.2 38
P-Site Identity: N.A. N.A. N.A. 33.3 6.6 20
P-Site Similarity: N.A. N.A. N.A. 53.3 6.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 65 0 12 0 0 0 0 0 6 0 6 0 0 0 % A
% Cys: 89 6 6 12 0 89 0 0 0 0 0 0 6 0 0 % C
% Asp: 0 0 0 0 6 0 6 12 71 12 6 0 59 0 0 % D
% Glu: 0 0 0 6 6 6 6 18 12 65 6 6 12 0 6 % E
% Phe: 0 0 0 0 6 0 0 0 0 0 6 0 0 6 6 % F
% Gly: 0 6 0 0 0 0 0 0 0 0 0 0 12 71 0 % G
% His: 0 12 0 0 0 0 12 0 0 0 0 0 0 0 0 % H
% Ile: 6 0 6 0 0 0 0 0 0 0 12 0 0 6 53 % I
% Lys: 0 0 0 53 0 0 0 0 0 0 0 0 0 0 6 % K
% Leu: 0 0 0 0 0 0 0 6 0 0 6 0 6 6 18 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 6 6 0 0 0 12 6 0 0 0 0 0 % N
% Pro: 0 0 0 0 71 0 12 12 0 0 6 83 0 12 6 % P
% Gln: 0 6 0 6 0 0 36 0 6 0 0 0 6 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % R
% Ser: 0 6 6 0 0 0 18 53 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 6 0 0 0 0 6 0 0 0 % T
% Val: 0 0 83 6 6 6 6 0 0 6 59 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _