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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERO1L All Species: 10.3
Human Site: S20 Identified Species: 14.17
UniProt: Q96HE7 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HE7 NP_055399.1 468 54393 S20 G A V W L L S S G H G E E Q P
Chimpanzee Pan troglodytes XP_509950 468 54427 L20 G A V W L L S L G H G E E Q P
Rhesus Macaque Macaca mulatta XP_001103965 468 54383 S20 G A V W L L S S G H G E Q Q P
Dog Lupus familis XP_547813 468 54343 P20 G A V W L L G P S H G E Q R P
Cat Felis silvestris
Mouse Mus musculus Q8R180 464 54066 L20 G V V W L L R L G H G E E R R
Rat Rattus norvegicus Q8R4A1 464 54000 S20 G V V W L L R S G Q G E E Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515503 465 53870 S17 E V L K F G T S S R I L C L K
Chicken Gallus gallus XP_421473 463 52908 L18 L G F A A L L L P A L P R G S
Frog Xenopus laevis Q6DD71 465 53720 W16 F L F S L L V W G T I A Q E A
Zebra Danio Brachydanio rerio Q7T3D1 489 56571 L12 V L L L G L F L T S V H V T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3A6 483 55641 G29 L L W T D T T G G Y F A A I D
Honey Bee Apis mellifera XP_623933 471 55049 V24 T V F S P S I V H S N Y F N T
Nematode Worm Caenorhab. elegans Q7YTU4 478 55136 I14 Q L I V L S L I I I V V N T Q
Sea Urchin Strong. purpuratus XP_796844 897 101920 T437 Y S S S G T S T F S G N A K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C7S7 469 53812 G43 S R T N S N V G F F F S D R N
Baker's Yeast Sacchar. cerevisiae Q03103 563 65014 I25 A T S N N S Y I A T D Q T Q N
Red Bread Mold Neurospora crassa Q7SEY9 668 75589 F13 R L F Y L S L F A L W S P E A
Conservation
Percent
Protein Identity: 100 99.5 98.7 96.3 N.A. 91.8 91.4 N.A. 84.6 77.7 70.9 62.1 N.A. 46.1 48.4 41.4 29.3
Protein Similarity: 100 99.5 99.3 97.8 N.A. 95.9 95.7 N.A. 90.1 85.4 83.9 75.4 N.A. 64.1 65.6 60.8 37.6
P-Site Identity: 100 93.3 93.3 66.6 N.A. 66.6 73.3 N.A. 6.6 6.6 20 6.6 N.A. 6.6 0 6.6 13.3
P-Site Similarity: 100 93.3 100 80 N.A. 73.3 73.3 N.A. 20 6.6 33.3 13.3 N.A. 20 0 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 37.9 22.5 22.1
Protein Similarity: N.A. N.A. N.A. 55.6 41.2 38
P-Site Identity: N.A. N.A. N.A. 0 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 24 0 6 6 0 0 0 12 6 0 12 12 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % C
% Asp: 0 0 0 0 6 0 0 0 0 0 6 0 6 0 6 % D
% Glu: 6 0 0 0 0 0 0 0 0 0 0 36 24 12 0 % E
% Phe: 6 0 24 0 6 0 6 6 12 6 12 0 6 0 0 % F
% Gly: 36 6 0 0 12 6 6 12 42 0 42 0 0 6 0 % G
% His: 0 0 0 0 0 0 0 0 6 30 0 6 0 0 0 % H
% Ile: 0 0 6 0 0 0 6 12 6 6 12 0 0 6 0 % I
% Lys: 0 0 0 6 0 0 0 0 0 0 0 0 0 6 12 % K
% Leu: 12 30 12 6 53 53 18 24 0 6 6 6 0 6 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 12 6 6 0 0 0 0 6 6 6 6 12 % N
% Pro: 0 0 0 0 6 0 0 6 6 0 0 6 6 0 24 % P
% Gln: 6 0 0 0 0 0 0 0 0 6 0 6 18 30 12 % Q
% Arg: 6 6 0 0 0 0 12 0 0 6 0 0 6 18 6 % R
% Ser: 6 6 12 18 6 24 24 24 12 18 0 12 0 0 6 % S
% Thr: 6 6 6 6 0 12 12 6 6 12 0 0 6 12 12 % T
% Val: 6 24 36 6 0 0 12 6 0 0 12 6 6 0 0 % V
% Trp: 0 0 6 36 0 0 0 6 0 0 6 0 0 0 0 % W
% Tyr: 6 0 0 6 0 0 6 0 0 6 0 6 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _