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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERO1L All Species: 43.94
Human Site: T293 Identified Species: 60.42
UniProt: Q96HE7 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HE7 NP_055399.1 468 54393 T293 Q R F D G I L T E G E G P R R
Chimpanzee Pan troglodytes XP_509950 468 54427 T293 Q R F D G I L T E G E G P R R
Rhesus Macaque Macaca mulatta XP_001103965 468 54383 T293 Q R F D G I L T E G E G P R R
Dog Lupus familis XP_547813 468 54343 T293 Q R F D G I L T E G E G P R R
Cat Felis silvestris
Mouse Mus musculus Q8R180 464 54066 T289 Q R F D G I L T E G E G P R R
Rat Rattus norvegicus Q8R4A1 464 54000 T289 Q R F D G V L T E G E G P R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515503 465 53870 T290 Q R F D A V L T E G E G P R R
Chicken Gallus gallus XP_421473 463 52908 T288 Q R F D E V V T R G E G P R R
Frog Xenopus laevis Q6DD71 465 53720 T291 K R F D A T L T H G E G P K R
Zebra Danio Brachydanio rerio Q7T3D1 489 56571 T284 Q R F D E D L T K G E G P K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3A6 483 55641 S303 K E F K R R F S P E T T S G E
Honey Bee Apis mellifera XP_623933 471 55049 F295 L Q E F Q K R F S P E E T G S
Nematode Worm Caenorhab. elegans Q7YTU4 478 55136 W288 A G R F G T K W S W E G P Q R
Sea Urchin Strong. purpuratus XP_796844 897 101920 T719 S R F D P E T T D G E G P I R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C7S7 469 53812 N313 Q A E Y D T G N H A E D L K T
Baker's Yeast Sacchar. cerevisiae Q03103 563 65014 S293 Q P Y L P E F S F C D L V N K
Red Bread Mold Neurospora crassa Q7SEY9 668 75589 L292 H A S I S T H L C W D F L N Q
Conservation
Percent
Protein Identity: 100 99.5 98.7 96.3 N.A. 91.8 91.4 N.A. 84.6 77.7 70.9 62.1 N.A. 46.1 48.4 41.4 29.3
Protein Similarity: 100 99.5 99.3 97.8 N.A. 95.9 95.7 N.A. 90.1 85.4 83.9 75.4 N.A. 64.1 65.6 60.8 37.6
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. 86.6 73.3 66.6 73.3 N.A. 6.6 6.6 33.3 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 86.6 80 86.6 N.A. 20 13.3 40 66.6
Percent
Protein Identity: N.A. N.A. N.A. 37.9 22.5 22.1
Protein Similarity: N.A. N.A. N.A. 55.6 41.2 38
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 0
P-Site Similarity: N.A. N.A. N.A. 20 33.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 12 0 0 12 0 0 0 0 6 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 6 6 0 0 0 0 0 % C
% Asp: 0 0 0 65 6 6 0 0 6 0 12 6 0 0 0 % D
% Glu: 0 6 12 0 12 12 0 0 42 6 83 6 0 0 6 % E
% Phe: 0 0 71 12 0 0 12 6 6 0 0 6 0 0 0 % F
% Gly: 0 6 0 0 42 0 6 0 0 65 0 71 0 12 0 % G
% His: 6 0 0 0 0 0 6 0 12 0 0 0 0 0 0 % H
% Ile: 0 0 0 6 0 30 0 0 0 0 0 0 0 6 0 % I
% Lys: 12 0 0 6 0 6 6 0 6 0 0 0 0 18 6 % K
% Leu: 6 0 0 6 0 0 53 6 0 0 0 6 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 6 0 0 0 0 0 12 0 % N
% Pro: 0 6 0 0 12 0 0 0 6 6 0 0 71 0 0 % P
% Gln: 65 6 0 0 6 0 0 0 0 0 0 0 0 6 6 % Q
% Arg: 0 65 6 0 6 6 6 0 6 0 0 0 0 48 71 % R
% Ser: 6 0 6 0 6 0 0 12 12 0 0 0 6 0 6 % S
% Thr: 0 0 0 0 0 24 6 65 0 0 6 6 6 0 6 % T
% Val: 0 0 0 0 0 18 6 0 0 0 0 0 6 0 0 % V
% Trp: 0 0 0 0 0 0 0 6 0 12 0 0 0 0 0 % W
% Tyr: 0 0 6 6 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _