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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERO1L
All Species:
35.45
Human Site:
Y431
Identified Species:
48.75
UniProt:
Q96HE7
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HE7
NP_055399.1
468
54393
Y431
M
P
E
S
G
P
S
Y
E
F
H
L
T
R
Q
Chimpanzee
Pan troglodytes
XP_509950
468
54427
Y431
M
P
E
S
G
P
S
Y
E
F
H
L
T
R
Q
Rhesus Macaque
Macaca mulatta
XP_001103965
468
54383
Y431
M
P
E
S
G
P
S
Y
E
F
H
L
T
R
Q
Dog
Lupus familis
XP_547813
468
54343
Y431
M
P
E
S
G
P
S
Y
E
F
H
L
T
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8R180
464
54066
Y427
M
P
E
S
G
P
S
Y
E
F
Q
L
T
R
Q
Rat
Rattus norvegicus
Q8R4A1
464
54000
Y427
M
P
E
S
G
P
S
Y
E
F
Q
L
T
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515503
465
53870
Y428
I
P
E
S
G
P
S
Y
G
F
H
L
T
R
Q
Chicken
Gallus gallus
XP_421473
463
52908
Y426
I
P
E
S
G
P
S
Y
G
F
Q
L
T
R
Q
Frog
Xenopus laevis
Q6DD71
465
53720
S429
L
S
E
S
N
Q
P
S
A
F
H
L
T
R
Q
Zebra Danio
Brachydanio rerio
Q7T3D1
489
56571
S422
M
P
N
K
Q
H
Q
S
I
I
S
A
Q
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3A6
483
55641
P449
K
P
H
I
E
A
D
P
I
F
R
L
S
R
T
Honey Bee
Apis mellifera
XP_623933
471
55049
R437
T
L
N
N
F
N
R
R
K
F
F
L
E
R
S
Nematode Worm
Caenorhab. elegans
Q7YTU4
478
55136
S422
S
H
Y
K
Q
D
S
S
K
F
Q
L
T
R
N
Sea Urchin
Strong. purpuratus
XP_796844
897
101920
R855
K
S
K
L
T
L
D
R
G
E
I
V
A
L
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C7S7
469
53812
P438
K
M
V
H
D
M
S
P
D
V
E
R
L
M
E
Baker's Yeast
Sacchar. cerevisiae
Q03103
563
65014
N525
S
Y
L
D
L
P
R
N
I
W
E
L
S
L
M
Red Bread Mold
Neurospora crassa
Q7SEY9
668
75589
I455
T
S
S
E
T
D
E
I
P
F
K
L
K
R
T
Conservation
Percent
Protein Identity:
100
99.5
98.7
96.3
N.A.
91.8
91.4
N.A.
84.6
77.7
70.9
62.1
N.A.
46.1
48.4
41.4
29.3
Protein Similarity:
100
99.5
99.3
97.8
N.A.
95.9
95.7
N.A.
90.1
85.4
83.9
75.4
N.A.
64.1
65.6
60.8
37.6
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
80
53.3
13.3
N.A.
26.6
20
33.3
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
86.6
60
13.3
N.A.
33.3
33.3
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.9
22.5
22.1
Protein Similarity:
N.A.
N.A.
N.A.
55.6
41.2
38
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
6
0
0
6
0
0
6
6
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
6
6
12
12
0
6
0
0
0
0
0
0
% D
% Glu:
0
0
53
6
6
0
6
0
36
6
12
0
6
0
6
% E
% Phe:
0
0
0
0
6
0
0
0
0
77
6
0
0
0
6
% F
% Gly:
0
0
0
0
48
0
0
0
18
0
0
0
0
0
0
% G
% His:
0
6
6
6
0
6
0
0
0
0
36
0
0
0
0
% H
% Ile:
12
0
0
6
0
0
0
6
18
6
6
0
0
0
0
% I
% Lys:
18
0
6
12
0
0
0
0
12
0
6
0
6
0
0
% K
% Leu:
6
6
6
6
6
6
0
0
0
0
0
83
6
12
0
% L
% Met:
42
6
0
0
0
6
0
0
0
0
0
0
0
6
6
% M
% Asn:
0
0
12
6
6
6
0
6
0
0
0
0
0
0
6
% N
% Pro:
0
59
0
0
0
53
6
12
6
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
12
6
6
0
0
0
24
0
6
0
53
% Q
% Arg:
0
0
0
0
0
0
12
12
0
0
6
6
0
77
0
% R
% Ser:
12
18
6
53
0
0
59
18
0
0
6
0
12
6
6
% S
% Thr:
12
0
0
0
12
0
0
0
0
0
0
0
59
0
12
% T
% Val:
0
0
6
0
0
0
0
0
0
6
0
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% W
% Tyr:
0
6
6
0
0
0
0
48
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _