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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM19 All Species: 30.61
Human Site: S197 Identified Species: 51.79
UniProt: Q96HH6 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HH6 NP_060749.2 336 36392 S197 S E V G P V L S K S S P R L I
Chimpanzee Pan troglodytes XP_509223 336 36329 S197 S E V G P V L S K S P P R L I
Rhesus Macaque Macaca mulatta XP_001117514 336 36436 S197 S E V G T V L S K S P P R L I
Dog Lupus familis XP_531680 335 35978 S196 S E V G P V L S K S P P R L I
Cat Felis silvestris
Mouse Mus musculus Q91W52 336 36278 S197 S E V A P V L S K S S P R L I
Rat Rattus norvegicus Q6P726 351 37732 S212 S E V A P V L S K S S P R L I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519027 208 22178 E80 P R L I T T W E K V P V G T H
Chicken Gallus gallus XP_416098 493 52256 S354 S E I G S V M S K S K P R L I
Frog Xenopus laevis Q6IR76 336 36715 S197 S E I G P V L S K S A P R L I
Zebra Danio Brachydanio rerio NP_001002098 322 35169 R194 P K L I T T W R D V P T G T N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648639 330 36105 P194 S V L S Q R D P V S I I T W R
Honey Bee Apis mellifera XP_623724 350 38717 A213 S E I G S V I A N K D P F L I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787408 257 28137 P129 I T T L E K V P R G T N G G I
Poplar Tree Populus trichocarpa XP_002324403 287 30190 T158 D A Q P R L I T T F K P V R R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 97.6 83.3 N.A. 87.1 84 N.A. 52.9 51.7 75.8 63.6 N.A. 45.2 43.7 N.A. 36
Protein Similarity: 100 99.1 99.1 88.6 N.A. 94.3 91.7 N.A. 58.3 61.4 89.2 77.9 N.A. 68.4 66 N.A. 50.8
P-Site Identity: 100 93.3 86.6 93.3 N.A. 93.3 93.3 N.A. 6.6 73.3 86.6 0 N.A. 13.3 46.6 N.A. 6.6
P-Site Similarity: 100 93.3 86.6 93.3 N.A. 93.3 93.3 N.A. 13.3 86.6 100 13.3 N.A. 20 66.6 N.A. 26.6
Percent
Protein Identity: 34.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 51.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 15 0 0 0 8 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 8 0 8 0 8 0 0 0 0 % D
% Glu: 0 65 0 0 8 0 0 8 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % F
% Gly: 0 0 0 50 0 0 0 0 0 8 0 0 22 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 8 0 22 15 0 0 15 0 0 0 8 8 0 0 72 % I
% Lys: 0 8 0 0 0 8 0 0 65 8 15 0 0 0 0 % K
% Leu: 0 0 22 8 0 8 50 0 0 0 0 0 0 65 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 8 % N
% Pro: 15 0 0 8 43 0 0 15 0 0 36 72 0 0 0 % P
% Gln: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 8 8 0 8 8 0 0 0 58 8 15 % R
% Ser: 72 0 0 8 15 0 0 58 0 65 22 0 0 0 0 % S
% Thr: 0 8 8 0 22 15 0 8 8 0 8 8 8 15 0 % T
% Val: 0 8 43 0 0 65 8 0 8 15 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 15 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _