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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM19
All Species:
22.42
Human Site:
S287
Identified Species:
37.95
UniProt:
Q96HH6
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HH6
NP_060749.2
336
36392
S287
Q
Y
T
G
L
D
E
S
T
G
M
V
V
N
S
Chimpanzee
Pan troglodytes
XP_509223
336
36329
S287
Q
Y
T
G
L
D
E
S
T
G
M
V
V
N
S
Rhesus Macaque
Macaca mulatta
XP_001117514
336
36436
S287
Q
Y
T
G
L
D
E
S
T
G
M
V
V
N
S
Dog
Lupus familis
XP_531680
335
35978
S286
Q
F
T
G
L
D
E
S
T
G
M
V
V
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91W52
336
36278
R287
Q
F
S
G
L
D
E
R
T
G
L
V
V
S
S
Rat
Rattus norvegicus
Q6P726
351
37732
S302
Q
F
S
G
L
D
E
S
T
G
L
V
V
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519027
208
22178
P167
T
G
L
V
V
N
H
P
R
N
A
V
R
H
I
Chicken
Gallus gallus
XP_416098
493
52256
N444
Q
Y
S
G
F
D
K
N
T
S
M
V
V
N
Y
Frog
Xenopus laevis
Q6IR76
336
36715
S287
Q
Y
S
G
Y
D
E
S
T
G
K
I
V
N
H
Zebra Danio
Brachydanio rerio
NP_001002098
322
35169
E281
I
R
K
V
V
S
Y
E
S
P
S
V
K
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648639
330
36105
E282
Q
F
S
G
I
N
E
E
G
K
I
V
D
T
P
Honey Bee
Apis mellifera
XP_623724
350
38717
K305
Q
Y
S
G
I
N
E
K
G
F
I
V
E
H
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787408
257
28137
S216
H
K
V
V
H
Q
A
S
P
T
T
E
H
I
S
Poplar Tree
Populus trichocarpa
XP_002324403
287
30190
V245
F
C
T
V
R
N
K
V
V
G
K
P
G
P
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.6
83.3
N.A.
87.1
84
N.A.
52.9
51.7
75.8
63.6
N.A.
45.2
43.7
N.A.
36
Protein Similarity:
100
99.1
99.1
88.6
N.A.
94.3
91.7
N.A.
58.3
61.4
89.2
77.9
N.A.
68.4
66
N.A.
50.8
P-Site Identity:
100
100
100
93.3
N.A.
66.6
73.3
N.A.
6.6
60
66.6
6.6
N.A.
26.6
33.3
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
26.6
80
80
20
N.A.
60
66.6
N.A.
13.3
Percent
Protein Identity:
34.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
58
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
65
15
0
0
0
8
8
0
0
% E
% Phe:
8
29
0
0
8
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
8
0
72
0
0
0
0
15
58
0
0
8
0
0
% G
% His:
8
0
0
0
8
0
8
0
0
0
0
0
8
15
8
% H
% Ile:
8
0
0
0
15
0
0
0
0
0
15
8
0
8
15
% I
% Lys:
0
8
8
0
0
0
15
8
0
8
15
0
8
0
0
% K
% Leu:
0
0
8
0
43
0
0
0
0
0
15
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
36
0
0
0
0
% M
% Asn:
0
0
0
0
0
29
0
8
0
8
0
0
0
43
0
% N
% Pro:
0
0
0
0
0
0
0
8
8
8
0
8
0
8
15
% P
% Gln:
72
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
8
0
0
8
8
0
0
0
8
8
0
% R
% Ser:
0
0
43
0
0
8
0
50
8
8
8
0
0
15
50
% S
% Thr:
8
0
36
0
0
0
0
0
58
8
8
0
0
8
8
% T
% Val:
0
0
8
29
15
0
0
8
8
0
0
79
58
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
43
0
0
8
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _