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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM19 All Species: 28.18
Human Site: S73 Identified Species: 47.69
UniProt: Q96HH6 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HH6 NP_060749.2 336 36392 S73 S N G L K K K S L D H S G A L
Chimpanzee Pan troglodytes XP_509223 336 36329 S73 S N G L K K K S L D H S G A L
Rhesus Macaque Macaca mulatta XP_001117514 336 36436 S73 S N G L K K K S L D H S G A L
Dog Lupus familis XP_531680 335 35978 D74 G F K K K S L D H S G A L G G
Cat Felis silvestris
Mouse Mus musculus Q91W52 336 36278 S73 C N G F K K K S L D H S G A L
Rat Rattus norvegicus Q6P726 351 37732 S88 C N G F K K K S L D H S G A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519027 208 22178
Chicken Gallus gallus XP_416098 493 52256 S230 T Q G F K K R S L D H S G A L
Frog Xenopus laevis Q6IR76 336 36715 S73 S H G I K K R S L D S S G A L
Zebra Danio Brachydanio rerio NP_001002098 322 35169 V74 G A M L V G F V L T M A N M S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648639 330 36105 G74 N R S G A A L G I L V A F I L
Honey Bee Apis mellifera XP_623724 350 38717 S89 F W S W K R K S L N I S G A I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787408 257 28137 L9 V M G V I M T L S S Y S H F L
Poplar Tree Populus trichocarpa XP_002324403 287 30190 I38 T G A V A G F I V M T L H F A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 97.6 83.3 N.A. 87.1 84 N.A. 52.9 51.7 75.8 63.6 N.A. 45.2 43.7 N.A. 36
Protein Similarity: 100 99.1 99.1 88.6 N.A. 94.3 91.7 N.A. 58.3 61.4 89.2 77.9 N.A. 68.4 66 N.A. 50.8
P-Site Identity: 100 100 100 6.6 N.A. 86.6 86.6 N.A. 0 73.3 73.3 13.3 N.A. 6.6 46.6 N.A. 20
P-Site Similarity: 100 100 100 13.3 N.A. 86.6 86.6 N.A. 0 86.6 93.3 20 N.A. 26.6 66.6 N.A. 33.3
Percent
Protein Identity: 34.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 51.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 20 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 15 8 0 0 0 0 0 22 0 58 8 % A
% Cys: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 0 50 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 8 8 0 22 0 0 15 0 0 0 0 0 8 15 0 % F
% Gly: 15 8 58 8 0 15 0 8 0 0 8 0 58 8 8 % G
% His: 0 8 0 0 0 0 0 0 8 0 43 0 15 0 0 % H
% Ile: 0 0 0 8 8 0 0 8 8 0 8 0 0 8 8 % I
% Lys: 0 0 8 8 65 50 43 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 29 0 0 15 8 65 8 0 8 8 0 65 % L
% Met: 0 8 8 0 0 8 0 0 0 8 8 0 0 8 0 % M
% Asn: 8 36 0 0 0 0 0 0 0 8 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 8 15 0 0 0 0 0 0 0 0 % R
% Ser: 29 0 15 0 0 8 0 58 8 15 8 65 0 0 8 % S
% Thr: 15 0 0 0 0 0 8 0 0 8 8 0 0 0 0 % T
% Val: 8 0 0 15 8 0 0 8 8 0 8 0 0 0 0 % V
% Trp: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _