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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM19
All Species:
31.52
Human Site:
S77
Identified Species:
53.33
UniProt:
Q96HH6
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HH6
NP_060749.2
336
36392
S77
K
K
K
S
L
D
H
S
G
A
L
G
G
L
V
Chimpanzee
Pan troglodytes
XP_509223
336
36329
S77
K
K
K
S
L
D
H
S
G
A
L
G
G
L
V
Rhesus Macaque
Macaca mulatta
XP_001117514
336
36436
S77
K
K
K
S
L
D
H
S
G
A
L
G
G
L
V
Dog
Lupus familis
XP_531680
335
35978
A78
K
S
L
D
H
S
G
A
L
G
G
L
V
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91W52
336
36278
S77
K
K
K
S
L
D
H
S
G
A
L
G
G
L
V
Rat
Rattus norvegicus
Q6P726
351
37732
S92
K
K
K
S
L
D
H
S
G
A
L
G
G
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519027
208
22178
Chicken
Gallus gallus
XP_416098
493
52256
S234
K
K
R
S
L
D
H
S
G
A
L
A
G
L
V
Frog
Xenopus laevis
Q6IR76
336
36715
S77
K
K
R
S
L
D
S
S
G
A
L
G
G
L
L
Zebra Danio
Brachydanio rerio
NP_001002098
322
35169
A78
V
G
F
V
L
T
M
A
N
M
S
F
F
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648639
330
36105
A78
A
A
L
G
I
L
V
A
F
I
L
S
I
A
S
Honey Bee
Apis mellifera
XP_623724
350
38717
S93
K
R
K
S
L
N
I
S
G
A
I
S
G
L
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787408
257
28137
S13
I
M
T
L
S
S
Y
S
H
F
L
C
L
V
A
Poplar Tree
Populus trichocarpa
XP_002324403
287
30190
L42
A
G
F
I
V
M
T
L
H
F
A
I
S
Y
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.6
83.3
N.A.
87.1
84
N.A.
52.9
51.7
75.8
63.6
N.A.
45.2
43.7
N.A.
36
Protein Similarity:
100
99.1
99.1
88.6
N.A.
94.3
91.7
N.A.
58.3
61.4
89.2
77.9
N.A.
68.4
66
N.A.
50.8
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
0
86.6
80
13.3
N.A.
6.6
60
N.A.
13.3
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
0
93.3
93.3
20
N.A.
20
80
N.A.
26.6
Percent
Protein Identity:
34.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
0
0
0
0
22
0
58
8
8
0
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
8
0
50
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
15
0
0
0
0
0
8
15
0
8
8
0
8
% F
% Gly:
0
15
0
8
0
0
8
0
58
8
8
43
58
0
8
% G
% His:
0
0
0
0
8
0
43
0
15
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
8
0
8
0
0
8
8
8
8
0
0
% I
% Lys:
65
50
43
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
15
8
65
8
0
8
8
0
65
8
8
58
8
% L
% Met:
0
8
0
0
0
8
8
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
15
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
8
0
58
8
15
8
65
0
0
8
15
8
0
8
% S
% Thr:
0
0
8
0
0
8
8
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
8
8
0
8
0
0
0
0
0
8
15
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _