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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM19
All Species:
33.94
Human Site:
T206
Identified Species:
57.44
UniProt:
Q96HH6
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HH6
NP_060749.2
336
36392
T206
S
S
P
R
L
I
T
T
W
E
K
V
P
V
G
Chimpanzee
Pan troglodytes
XP_509223
336
36329
T206
S
P
P
R
L
I
T
T
W
E
K
V
P
V
G
Rhesus Macaque
Macaca mulatta
XP_001117514
336
36436
T206
S
P
P
R
L
I
T
T
W
E
K
V
P
V
G
Dog
Lupus familis
XP_531680
335
35978
T205
S
P
P
R
L
I
T
T
W
E
K
V
P
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91W52
336
36278
T206
S
S
P
R
L
I
T
T
W
E
K
V
P
V
G
Rat
Rattus norvegicus
Q6P726
351
37732
T221
S
S
P
R
L
I
T
T
W
E
K
V
P
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519027
208
22178
G89
V
P
V
G
T
H
G
G
I
T
L
V
G
V
I
Chicken
Gallus gallus
XP_416098
493
52256
T363
S
K
P
R
L
I
T
T
W
K
Q
V
P
V
G
Frog
Xenopus laevis
Q6IR76
336
36715
T206
S
A
P
R
L
I
T
T
W
E
K
V
P
V
G
Zebra Danio
Brachydanio rerio
NP_001002098
322
35169
G203
V
P
T
G
T
N
G
G
V
T
S
V
G
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648639
330
36105
V203
S
I
I
T
W
R
R
V
P
R
G
T
N
G
G
Honey Bee
Apis mellifera
XP_623724
350
38717
T222
K
D
P
F
L
I
T
T
F
K
R
V
P
R
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787408
257
28137
L138
G
T
N
G
G
I
S
L
V
G
T
L
M
S
F
Poplar Tree
Populus trichocarpa
XP_002324403
287
30190
A167
F
K
P
V
R
R
G
A
N
G
G
V
T
L
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.6
83.3
N.A.
87.1
84
N.A.
52.9
51.7
75.8
63.6
N.A.
45.2
43.7
N.A.
36
Protein Similarity:
100
99.1
99.1
88.6
N.A.
94.3
91.7
N.A.
58.3
61.4
89.2
77.9
N.A.
68.4
66
N.A.
50.8
P-Site Identity:
100
93.3
93.3
93.3
N.A.
100
100
N.A.
13.3
80
93.3
6.6
N.A.
13.3
53.3
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
100
100
N.A.
13.3
93.3
100
13.3
N.A.
13.3
73.3
N.A.
26.6
Percent
Protein Identity:
34.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% E
% Phe:
8
0
0
8
0
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
8
0
0
22
8
0
22
15
0
15
15
0
15
8
72
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
72
0
0
8
0
0
0
0
0
8
% I
% Lys:
8
15
0
0
0
0
0
0
0
15
50
0
0
0
0
% K
% Leu:
0
0
0
0
65
0
0
8
0
0
8
8
0
15
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
8
0
0
0
8
0
0
% N
% Pro:
0
36
72
0
0
0
0
0
8
0
0
0
65
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
58
8
15
8
0
0
8
8
0
0
8
0
% R
% Ser:
65
22
0
0
0
0
8
0
0
0
8
0
0
8
0
% S
% Thr:
0
8
8
8
15
0
65
65
0
15
8
8
8
0
0
% T
% Val:
15
0
8
8
0
0
0
8
15
0
0
86
0
65
0
% V
% Trp:
0
0
0
0
8
0
0
0
58
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _