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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SH3YL1 All Species: 14.55
Human Site: S249 Identified Species: 32
UniProt: Q96HL8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HL8 NP_001153069.1 342 37148 S249 P L S R P Q Q S S A P V Q L N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001117525 342 37123 S249 P L S R P Q Q S P A P V Q L N
Dog Lupus familis XP_848316 349 38086 S256 P L S R P Q P S P A Q V P P N
Cat Felis silvestris
Mouse Mus musculus O08641 340 37010 A247 P S S R P Q P A H P P V Q L N
Rat Rattus norvegicus B0BNA1 340 37021 S247 P S S R P Q P S R P P V Q L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516879 177 18397 G88 A I G I A G L G G G F E I G I
Chicken Gallus gallus Q8AXV0 367 41714 S271 D F G E S D Q S N G G F S C T
Frog Xenopus laevis Q6DFH5 335 36339 S245 S R P R S F P S S S G N D G Q
Zebra Danio Brachydanio rerio XP_694886 336 35953 S245 P P T Q K S A S S Y T P R T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q08012 211 24417 V122 S K F F L W V V K F N S L N E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32793 468 50883 L375 G R E R G Y S L G H G P T H P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.1 88.8 N.A. 92.4 92.4 N.A. 49.7 20.4 72.2 64.6 N.A. 23.3 N.A. N.A. N.A.
Protein Similarity: 100 N.A. 99.4 93.6 N.A. 95.6 95.9 N.A. 51.1 40 82.1 77.1 N.A. 37.1 N.A. N.A. N.A.
P-Site Identity: 100 N.A. 93.3 66.6 N.A. 66.6 73.3 N.A. 0 13.3 20 20 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 93.3 66.6 N.A. 73.3 73.3 N.A. 6.6 20 26.6 40 N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 36.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 51.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 10 0 10 10 0 28 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 10 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 0 10 10 0 0 0 0 0 0 0 10 0 0 10 % E
% Phe: 0 10 10 10 0 10 0 0 0 10 10 10 0 0 0 % F
% Gly: 10 0 19 0 10 10 0 10 19 19 28 0 0 19 0 % G
% His: 0 0 0 0 0 0 0 0 10 10 0 0 0 10 0 % H
% Ile: 0 10 0 10 0 0 0 0 0 0 0 0 10 0 10 % I
% Lys: 0 10 0 0 10 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 0 28 0 0 10 0 10 10 0 0 0 0 10 37 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 10 10 0 10 46 % N
% Pro: 55 10 10 0 46 0 37 0 19 19 37 19 10 10 10 % P
% Gln: 0 0 0 10 0 46 28 0 0 0 10 0 37 0 19 % Q
% Arg: 0 19 0 64 0 0 0 0 10 0 0 0 10 0 0 % R
% Ser: 19 19 46 0 19 10 10 64 28 10 0 10 10 0 0 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 10 0 10 10 10 % T
% Val: 0 0 0 0 0 0 10 10 0 0 0 46 0 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _