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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3YL1
All Species:
26.36
Human Site:
T175
Identified Species:
58
UniProt:
Q96HL8
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HL8
NP_001153069.1
342
37148
T175
C
L
I
E
R
K
E
T
N
R
K
F
Y
C
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117525
342
37123
T175
C
L
I
E
R
K
E
T
N
R
K
F
Y
C
Q
Dog
Lupus familis
XP_848316
349
38086
T182
C
L
I
E
R
K
E
T
N
R
K
F
Y
C
Q
Cat
Felis silvestris
Mouse
Mus musculus
O08641
340
37010
T175
C
L
I
E
R
K
E
T
N
R
K
F
Y
C
Q
Rat
Rattus norvegicus
B0BNA1
340
37021
T175
C
L
I
E
R
K
E
T
N
R
K
F
Y
C
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516879
177
18397
I18
E
A
R
K
A
A
K
I
L
R
E
F
T
E
I
Chicken
Gallus gallus
Q8AXV0
367
41714
F190
L
R
Q
A
M
E
K
F
E
E
S
K
E
V
A
Frog
Xenopus laevis
Q6DFH5
335
36339
T175
G
L
I
E
R
K
E
T
N
R
K
F
Y
G
Q
Zebra Danio
Brachydanio rerio
XP_694886
336
35953
T175
Y
L
I
E
R
K
D
T
N
R
K
F
Y
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q08012
211
24417
Y52
E
G
L
I
P
S
N
Y
I
E
M
K
N
H
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32793
468
50883
A179
A
I
L
E
R
R
E
A
N
R
K
F
Y
G
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.1
88.8
N.A.
92.4
92.4
N.A.
49.7
20.4
72.2
64.6
N.A.
23.3
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
99.4
93.6
N.A.
95.6
95.9
N.A.
51.1
40
82.1
77.1
N.A.
37.1
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
0
86.6
73.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
33.3
13.3
86.6
86.6
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
10
10
10
0
10
0
0
0
0
0
0
10
% A
% Cys:
46
0
0
0
0
0
0
0
0
0
0
0
0
46
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
19
% D
% Glu:
19
0
0
73
0
10
64
0
10
19
10
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
82
0
0
0
% F
% Gly:
10
10
0
0
0
0
0
0
0
0
0
0
0
28
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
10
64
10
0
0
0
10
10
0
0
0
0
0
10
% I
% Lys:
0
0
0
10
0
64
19
0
0
0
73
19
0
0
10
% K
% Leu:
10
64
19
0
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
73
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
55
% Q
% Arg:
0
10
10
0
73
10
0
0
0
82
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
64
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
10
0
0
0
0
73
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _