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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM176A
All Species:
6.36
Human Site:
Y147
Identified Species:
23.33
UniProt:
Q96HP8
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HP8
NP_060957.2
235
26116
Y147
F
R
Y
G
Y
S
Y
Y
N
S
A
C
R
I
S
Chimpanzee
Pan troglodytes
XP_519474
350
37690
Y147
F
R
Y
G
Y
S
Y
Y
N
S
A
C
H
I
S
Rhesus Macaque
Macaca mulatta
XP_001103245
321
34816
Y235
D
F
R
Y
G
Y
Y
Y
D
S
I
C
H
I
S
Dog
Lupus familis
XP_532758
241
26277
L151
F
Y
R
H
R
F
Y
L
R
D
F
I
C
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCS1
244
26578
L154
L
N
F
Y
W
Y
F
L
G
D
D
V
C
Q
R
Rat
Rattus norvegicus
Q4G068
243
26595
L154
F
N
N
Y
W
Y
Y
L
R
D
D
V
C
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519714
324
34414
F165
F
V
W
Q
P
D
G
F
Y
Y
M
D
S
V
C
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.2
62.9
59.7
N.A.
54
55.9
N.A.
28.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
61.4
66.3
71.3
N.A.
70.4
70.3
N.A.
42.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
40
13.3
N.A.
0
20
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
46.6
13.3
N.A.
20
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
29
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
43
43
0
15
% C
% Asp:
15
0
0
0
0
15
0
0
15
43
29
15
0
15
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
72
15
15
0
0
15
15
15
0
0
15
0
0
0
0
% F
% Gly:
0
0
0
29
15
0
15
0
15
0
0
0
0
0
0
% G
% His:
0
0
0
15
0
0
0
0
0
0
0
0
29
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
15
15
0
43
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% K
% Leu:
15
0
0
0
0
0
0
43
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% M
% Asn:
0
29
15
0
0
0
0
0
29
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
15
0
0
0
0
0
0
0
0
0
15
0
% Q
% Arg:
0
29
29
0
15
0
0
0
29
0
0
0
15
0
15
% R
% Ser:
0
0
0
0
0
29
0
0
0
43
0
0
15
0
58
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
15
0
0
0
0
0
0
0
0
0
29
0
15
15
% V
% Trp:
0
0
15
0
29
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
29
43
29
43
72
43
15
15
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _