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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED30 All Species: 37.58
Human Site: T40 Identified Species: 75.15
UniProt: Q96HR3 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HR3 NP_542382.1 178 20277 T40 L C R I G Q E T V Q D I V Y R
Chimpanzee Pan troglodytes XP_001140775 153 17096 T40 L C R I G Q E T V Q D I V Y R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539144 178 20252 T40 L C R I G Q E T V Q D I V Y R
Cat Felis silvestris
Mouse Mus musculus Q9CQI9 178 20340 T40 L C R I G Q E T V Q D I V Y R
Rat Rattus norvegicus NP_001124011 143 16327 T40 L C R I G Q E T V Q D I V Y R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509173 316 34689 R111 G A L V W A P R G E M A T G E
Chicken Gallus gallus XP_418397 179 20395 T39 L C R I G Q E T V Q D I V F R
Frog Xenopus laevis Q0IHI6 184 20853 T44 L C R I G Q E T V Q D I V F R
Zebra Danio Brachydanio rerio Q6PC45 174 20183 T35 L C R I G Q E T V Q D I V L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W0P3 318 35283 Q90 Q H Q M Q Q Q Q Q Q Q M M Q Q
Honey Bee Apis mellifera XP_396322 294 32976 T154 L C R F G Q E T V Q D I V S R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790489 177 20120 S58 G R S N T Q Q S H Q D K I T K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.7 N.A. 97.1 N.A. 94.9 75.8 N.A. 37 87.7 81.5 76.4 N.A. 21 32.3 N.A. 41
Protein Similarity: 100 84.8 N.A. 98.8 N.A. 97.7 78.6 N.A. 45.8 92.7 88 84.2 N.A. 34.2 41.1 N.A. 62.3
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 0 93.3 93.3 93.3 N.A. 13.3 86.6 N.A. 20
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 13.3 100 100 93.3 N.A. 53.3 86.6 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 9 0 0 0 0 0 9 0 0 0 % A
% Cys: 0 75 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 84 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 75 0 0 9 0 0 0 0 9 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 0 0 0 17 0 % F
% Gly: 17 0 0 0 75 0 0 0 9 0 0 0 0 9 0 % G
% His: 0 9 0 0 0 0 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 0 0 67 0 0 0 0 0 0 0 75 9 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % K
% Leu: 75 0 9 0 0 0 0 0 0 0 0 0 0 9 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 9 9 9 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 9 0 9 92 17 9 9 92 9 0 0 9 9 % Q
% Arg: 0 9 75 0 0 0 0 9 0 0 0 0 0 0 75 % R
% Ser: 0 0 9 0 0 0 0 9 0 0 0 0 0 9 0 % S
% Thr: 0 0 0 0 9 0 0 75 0 0 0 0 9 9 0 % T
% Val: 0 0 0 9 0 0 0 0 75 0 0 0 75 0 0 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 42 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _