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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED30 All Species: 25.15
Human Site: Y46 Identified Species: 50.3
UniProt: Q96HR3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HR3 NP_542382.1 178 20277 Y46 E T V Q D I V Y R T M E I F Q
Chimpanzee Pan troglodytes XP_001140775 153 17096 Y46 E T V Q D I V Y R T M E I F Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539144 178 20252 Y46 E T V Q D I V Y R T M E I F Q
Cat Felis silvestris
Mouse Mus musculus Q9CQI9 178 20340 Y46 E T V Q D I V Y R T M E I F Q
Rat Rattus norvegicus NP_001124011 143 16327 Y46 E T V Q D I V Y R T M E I F Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509173 316 34689 G117 P R G E M A T G E I L R R G R
Chicken Gallus gallus XP_418397 179 20395 F45 E T V Q D I V F R T M E I F Q
Frog Xenopus laevis Q0IHI6 184 20853 F50 E T V Q D I V F R T M E I F Q
Zebra Danio Brachydanio rerio Q6PC45 174 20183 L41 E T V Q D I V L R T M E I F Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W0P3 318 35283 Q96 Q Q Q Q Q M M Q Q Q M M V P Q
Honey Bee Apis mellifera XP_396322 294 32976 S160 E T V Q D I V S R T L E V F Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790489 177 20120 T64 Q S H Q D K I T K L Q D I T K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.7 N.A. 97.1 N.A. 94.9 75.8 N.A. 37 87.7 81.5 76.4 N.A. 21 32.3 N.A. 41
Protein Similarity: 100 84.8 N.A. 98.8 N.A. 97.7 78.6 N.A. 45.8 92.7 88 84.2 N.A. 34.2 41.1 N.A. 62.3
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 0 93.3 93.3 93.3 N.A. 20 80 N.A. 20
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 20 100 100 93.3 N.A. 53.3 93.3 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 84 0 0 0 0 0 0 9 0 0 0 % D
% Glu: 75 0 0 9 0 0 0 0 9 0 0 75 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 17 0 0 0 0 0 75 0 % F
% Gly: 0 0 9 0 0 0 0 9 0 0 0 0 0 9 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 75 9 0 0 9 0 0 75 0 0 % I
% Lys: 0 0 0 0 0 9 0 0 9 0 0 0 0 0 9 % K
% Leu: 0 0 0 0 0 0 0 9 0 9 17 0 0 0 0 % L
% Met: 0 0 0 0 9 9 9 0 0 0 75 9 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % P
% Gln: 17 9 9 92 9 0 0 9 9 9 9 0 0 0 84 % Q
% Arg: 0 9 0 0 0 0 0 0 75 0 0 9 9 0 9 % R
% Ser: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 0 % S
% Thr: 0 75 0 0 0 0 9 9 0 75 0 0 0 9 0 % T
% Val: 0 0 75 0 0 0 75 0 0 0 0 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 42 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _