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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NAF1 All Species: 4.55
Human Site: T374 Identified Species: 10
UniProt: Q96HR8 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HR8 NP_001122403.1 494 53703 T374 G Y R N R E F T R G F S R A R
Chimpanzee Pan troglodytes XP_517514 494 53703 T374 G Y R N R E F T R G F S R A R
Rhesus Macaque Macaca mulatta XP_001098118 497 54102 R378 Y R N R E F T R G F S R G R Y
Dog Lupus familis XP_532709 418 46604 F315 G T P P S P R F Y N S E H M V
Cat Felis silvestris
Mouse Mus musculus Q3UMQ8 489 53227 R367 Y H H R E F S R G F A R G R Y
Rat Rattus norvegicus Q52KK4 457 49745 R353 Y S R G S H G R P P P Q Q Y Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510654 398 44132 F295 R P A P Q Q Y F P S Q H M A S
Chicken Gallus gallus XP_001233313 452 50029 G349 D P F P S P S G P S G F P R P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696744 503 56033 E387 L A K Q K L K E Q K R R Q Q N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJ62 564 62252 R459 Q R G R R G Q R E S F R Q S Q
Honey Bee Apis mellifera XP_001121734 471 54616 N353 N R Q F F F E N Q S Q T L W P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 94.9 69.6 N.A. 73.4 75.5 N.A. 54.2 46.9 N.A. 39.9 N.A. 28.8 22.2 N.A. N.A.
Protein Similarity: 100 99.5 96.1 74.6 N.A. 81.3 82.5 N.A. 63.7 61.1 N.A. 56.8 N.A. 45 42.1 N.A. N.A.
P-Site Identity: 100 100 0 6.6 N.A. 0 6.6 N.A. 6.6 0 N.A. 0 N.A. 13.3 0 N.A. N.A.
P-Site Similarity: 100 100 0 6.6 N.A. 6.6 13.3 N.A. 26.6 0 N.A. 26.6 N.A. 33.3 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 0 0 0 0 0 0 10 0 0 28 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 19 19 10 10 10 0 0 10 0 0 0 % E
% Phe: 0 0 10 10 10 28 19 19 0 19 28 10 0 0 0 % F
% Gly: 28 0 10 10 0 10 10 10 19 19 10 0 19 0 0 % G
% His: 0 10 10 0 0 10 0 0 0 0 0 10 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 10 0 10 0 0 10 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % M
% Asn: 10 0 10 19 0 0 0 10 0 10 0 0 0 0 10 % N
% Pro: 0 19 10 28 0 19 0 0 28 10 10 0 10 0 19 % P
% Gln: 10 0 10 10 10 10 10 0 19 0 19 10 28 10 10 % Q
% Arg: 10 28 28 28 28 0 10 37 19 0 10 37 19 28 19 % R
% Ser: 0 10 0 0 28 0 19 0 0 37 19 19 0 10 10 % S
% Thr: 0 10 0 0 0 0 10 19 0 0 0 10 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 28 19 0 0 0 0 10 0 10 0 0 0 0 10 28 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _