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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NAF1 All Species: 4.85
Human Site: Y422 Identified Species: 10.67
UniProt: Q96HR8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HR8 NP_001122403.1 494 53703 Y422 N N P I M P Q Y P F P L P V F
Chimpanzee Pan troglodytes XP_517514 494 53703 Y422 D N P I M P Q Y P F P L P M F
Rhesus Macaque Macaca mulatta XP_001098118 497 54102 P426 N P I M P Q Y P F P L P M F D
Dog Lupus familis XP_532709 418 46604 L363 L P P P L P P L P P P P P P A
Cat Felis silvestris
Mouse Mus musculus Q3UMQ8 489 53227 P415 N P V M P H Y P F P P P M F D
Rat Rattus norvegicus Q52KK4 457 49745 P401 D M H N F P L P P P P P P P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510654 398 44132 H343 P P V F D L H H F P P P P P P
Chicken Gallus gallus XP_001233313 452 50029 V397 Q Y P F P P P V F G S V N E M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696744 503 56033 H435 H N R G G G F H S N F H A H P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJ62 564 62252 A507 Q N Y H Q A A A N F N M A Q Q
Honey Bee Apis mellifera XP_001121734 471 54616 Y401 L Y S S R N Y Y N E D N S T T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 94.9 69.6 N.A. 73.4 75.5 N.A. 54.2 46.9 N.A. 39.9 N.A. 28.8 22.2 N.A. N.A.
Protein Similarity: 100 99.5 96.1 74.6 N.A. 81.3 82.5 N.A. 63.7 61.1 N.A. 56.8 N.A. 45 42.1 N.A. N.A.
P-Site Identity: 100 86.6 6.6 33.3 N.A. 13.3 26.6 N.A. 13.3 13.3 N.A. 6.6 N.A. 13.3 6.6 N.A. N.A.
P-Site Similarity: 100 100 13.3 40 N.A. 20 33.3 N.A. 20 20 N.A. 20 N.A. 20 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 10 10 0 0 0 0 19 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 19 0 0 0 10 0 0 0 0 0 10 0 0 0 19 % D
% Glu: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % E
% Phe: 0 0 0 19 10 0 10 0 37 28 10 0 0 19 19 % F
% Gly: 0 0 0 10 10 10 0 0 0 10 0 0 0 0 0 % G
% His: 10 0 10 10 0 10 10 19 0 0 0 10 0 10 0 % H
% Ile: 0 0 10 19 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 19 0 0 0 10 10 10 10 0 0 10 19 0 0 0 % L
% Met: 0 10 0 19 19 0 0 0 0 0 0 10 19 10 10 % M
% Asn: 28 37 0 10 0 10 0 0 19 10 10 10 10 0 0 % N
% Pro: 10 37 37 10 28 46 19 28 37 46 55 46 46 28 28 % P
% Gln: 19 0 0 0 10 10 19 0 0 0 0 0 0 10 10 % Q
% Arg: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 10 10 0 0 0 0 10 0 10 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % T
% Val: 0 0 19 0 0 0 0 10 0 0 0 10 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 19 10 0 0 0 28 28 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _