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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REEP6
All Species:
41.82
Human Site:
S76
Identified Species:
76.67
UniProt:
Q96HR9
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HR9
NP_612402.1
184
20733
S76
A
S
I
K
A
I
E
S
P
S
K
D
D
D
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095757
184
20648
S76
A
S
I
K
A
I
E
S
P
S
K
D
D
D
T
Dog
Lupus familis
XP_855124
414
44146
S72
A
S
I
K
A
I
E
S
P
S
K
E
D
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JM62
201
22185
S76
A
S
V
K
A
I
E
S
P
S
K
E
D
D
T
Rat
Rattus norvegicus
Q5XI60
211
23295
S76
A
S
V
K
A
I
E
S
P
N
K
E
D
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507345
189
21424
S77
I
S
I
K
A
I
E
S
P
N
K
D
D
D
T
Chicken
Gallus gallus
XP_001233336
302
33303
S190
V
S
I
K
A
I
E
S
P
N
K
D
D
D
T
Frog
Xenopus laevis
NP_001088158
188
21408
S76
I
S
I
K
A
I
E
S
Q
D
K
K
D
D
T
Zebra Danio
Brachydanio rerio
Q4KMI4
268
30092
Y106
K
E
R
E
I
D
E
Y
I
T
Q
A
K
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610936
178
20295
S85
I
S
I
H
A
I
E
S
S
T
K
Q
D
D
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780122
198
22388
S76
C
S
V
K
A
I
E
S
T
Q
K
D
D
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12402
180
20251
T81
L
S
L
V
A
L
K
T
P
T
S
T
D
D
T
Red Bread Mold
Neurospora crassa
Q871R7
168
19003
A76
P
G
Y
Y
S
L
N
A
L
F
T
A
S
K
Q
Conservation
Percent
Protein Identity:
100
N.A.
96.1
36.7
N.A.
73.1
69.6
N.A.
57.1
35
56.9
20.5
N.A.
46.2
N.A.
N.A.
50
Protein Similarity:
100
N.A.
98.3
39.6
N.A.
81.5
77.7
N.A.
73.5
45.7
75
30.2
N.A.
66.8
N.A.
N.A.
65.1
P-Site Identity:
100
N.A.
100
93.3
N.A.
86.6
80
N.A.
86.6
86.6
73.3
13.3
N.A.
66.6
N.A.
N.A.
73.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
93.3
73.3
33.3
N.A.
73.3
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.4
34.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50
50
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
0
0
0
85
0
0
8
0
0
0
16
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
8
0
39
85
93
0
% D
% Glu:
0
8
0
8
0
0
85
0
0
0
0
24
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
24
0
54
0
8
77
0
0
8
0
0
0
0
0
0
% I
% Lys:
8
0
0
70
0
0
8
0
0
0
77
8
8
8
0
% K
% Leu:
8
0
8
0
0
16
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
24
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
62
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
8
8
8
0
0
8
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
85
0
0
8
0
0
77
8
31
8
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
8
24
8
8
0
0
85
% T
% Val:
8
0
24
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _