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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGAM5 All Species: 22.12
Human Site: S69 Identified Species: 40.56
UniProt: Q96HS1 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HS1 NP_612642.1 289 32004 S69 W D R R E P L S L I N V R K R
Chimpanzee Pan troglodytes XP_509498 465 51564 S69 W D R R E P L S L I N V R K R
Rhesus Macaque Macaca mulatta XP_001083353 235 26735 L19 E P L S L I N L R K R N V E S
Dog Lupus familis XP_543346 289 31978 S69 W D R R E P L S L V N L R K R
Cat Felis silvestris
Mouse Mus musculus Q8BX10 288 31976 S68 W D R R E P L S L I N L K K R
Rat Rattus norvegicus Q562B5 288 32042 S68 W D R R E P L S L I N L K K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510978 229 26244 N13 R E P R S L I N L R K R N T E
Chicken Gallus gallus XP_415083 212 24106
Frog Xenopus laevis Q5FWM4 275 30968 S56 W D R R E P I S M V N L S K I
Zebra Danio Brachydanio rerio Q502L2 289 32155 P69 Y N W D K R E P S S M V N G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O46084 289 33147 A58 W D C R E P R A L V R P L R N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09422 284 32472 R63 W D K N W D F R D P I S L V D
Sea Urchin Strong. purpuratus XP_793164 286 31924 P65 T N W D K R D P E S L I N P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.7 79.9 93 N.A. 93.4 92.7 N.A. 70.9 64.3 65 64.7 N.A. 46 N.A. 42.5 53.6
Protein Similarity: 100 62.1 81.3 97.5 N.A. 96.1 96.8 N.A. 76.8 70.5 78.1 77.1 N.A. 61.9 N.A. 59.1 67.1
P-Site Identity: 100 100 0 86.6 N.A. 86.6 86.6 N.A. 13.3 0 60 6.6 N.A. 40 N.A. 13.3 0
P-Site Similarity: 100 100 6.6 100 N.A. 100 100 N.A. 33.3 0 86.6 33.3 N.A. 60 N.A. 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 62 0 16 0 8 8 0 8 0 0 0 0 0 8 % D
% Glu: 8 8 0 0 54 0 8 0 8 0 0 0 0 8 8 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 16 0 0 31 8 8 0 0 8 % I
% Lys: 0 0 8 0 16 0 0 0 0 8 8 0 16 47 8 % K
% Leu: 0 0 8 0 8 8 39 8 54 0 8 31 16 0 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % M
% Asn: 0 16 0 8 0 0 8 8 0 0 47 8 24 0 8 % N
% Pro: 0 8 8 0 0 54 0 16 0 8 0 8 0 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 47 62 0 16 8 8 8 8 16 8 24 8 39 % R
% Ser: 0 0 0 8 8 0 0 47 8 16 0 8 8 0 16 % S
% Thr: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % T
% Val: 0 0 0 0 0 0 0 0 0 24 0 24 8 8 0 % V
% Trp: 62 0 16 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _