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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PGAM5
All Species:
34.85
Human Site:
T121
Identified Species:
63.89
UniProt:
Q96HS1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HS1
NP_612642.1
289
32004
T121
L
E
K
D
R
T
L
T
P
L
G
R
E
Q
A
Chimpanzee
Pan troglodytes
XP_509498
465
51564
T121
L
E
K
D
R
T
L
T
P
L
G
R
E
Q
A
Rhesus Macaque
Macaca mulatta
XP_001083353
235
26735
R71
R
T
L
T
P
L
G
R
E
Q
A
E
L
T
G
Dog
Lupus familis
XP_543346
289
31978
T121
L
E
K
D
R
T
L
T
P
L
G
R
E
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX10
288
31976
T120
L
E
K
D
R
T
L
T
P
L
G
R
E
Q
A
Rat
Rattus norvegicus
Q562B5
288
32042
T120
M
E
K
D
R
T
L
T
P
L
G
R
E
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510978
229
26244
G65
D
R
T
L
T
P
L
G
R
E
Q
A
E
L
T
Chicken
Gallus gallus
XP_415083
212
24106
R48
R
T
L
T
P
L
G
R
E
Q
A
E
L
T
G
Frog
Xenopus laevis
Q5FWM4
275
30968
T108
T
D
F
D
R
V
L
T
P
L
G
R
E
Q
A
Zebra Danio
Brachydanio rerio
Q502L2
289
32155
T121
G
D
K
E
R
F
L
T
P
L
G
R
E
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46084
289
33147
T110
S
D
D
T
H
H
L
T
E
R
G
R
K
Q
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09422
284
32472
T115
D
H
E
V
K
M
L
T
P
L
G
R
E
Q
A
Sea Urchin
Strong. purpuratus
XP_793164
286
31924
T117
T
D
D
E
R
I
L
T
A
L
G
R
E
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.7
79.9
93
N.A.
93.4
92.7
N.A.
70.9
64.3
65
64.7
N.A.
46
N.A.
42.5
53.6
Protein Similarity:
100
62.1
81.3
97.5
N.A.
96.1
96.8
N.A.
76.8
70.5
78.1
77.1
N.A.
61.9
N.A.
59.1
67.1
P-Site Identity:
100
100
0
100
N.A.
100
93.3
N.A.
13.3
0
73.3
73.3
N.A.
40
N.A.
60
60
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
13.3
0
80
86.6
N.A.
53.3
N.A.
73.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
16
8
0
0
77
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
31
16
47
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
39
8
16
0
0
0
0
24
8
0
16
77
0
0
% E
% Phe:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
16
8
0
0
77
0
0
0
16
% G
% His:
0
8
0
0
8
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
47
0
8
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
31
0
16
8
0
16
85
0
0
70
0
0
16
8
0
% L
% Met:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
16
8
0
0
62
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
16
8
0
0
77
0
% Q
% Arg:
16
8
0
0
62
0
0
16
8
8
0
77
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
16
16
8
24
8
39
0
77
0
0
0
0
0
16
8
% T
% Val:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _