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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIRAS2
All Species:
26.67
Human Site:
S175
Identified Species:
39.11
UniProt:
Q96HU8
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HU8
NP_060064.2
199
22485
S175
L
E
K
R
R
T
V
S
L
Q
I
D
G
K
K
Chimpanzee
Pan troglodytes
XP_001142084
196
21944
E174
T
G
E
R
E
D
V
E
S
L
S
Q
G
E
E
Rhesus Macaque
Macaca mulatta
XP_001099006
198
22268
S174
L
E
T
R
R
N
M
S
L
N
I
D
G
K
R
Dog
Lupus familis
XP_541313
208
23428
S184
L
E
K
R
R
T
V
S
L
Q
I
D
G
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5PR73
199
22479
S175
L
E
K
R
R
T
V
S
L
Q
I
D
G
K
K
Rat
Rattus norvegicus
Q62636
184
20779
T169
V
R
Q
I
N
R
K
T
P
V
P
G
K
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513649
198
22370
C174
L
E
K
R
R
A
V
C
L
Q
V
D
G
K
K
Chicken
Gallus gallus
XP_423026
199
22563
S175
L
E
K
R
R
T
V
S
L
Q
I
D
G
K
K
Frog
Xenopus laevis
Q7ZXH7
184
20815
K168
L
V
R
Q
I
N
R
K
T
P
V
P
G
K
A
Zebra Danio
Brachydanio rerio
Q6TEN1
184
20809
K168
L
V
R
Q
I
N
R
K
T
P
V
T
G
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08645
184
20845
P169
R
Q
I
N
K
K
S
P
E
K
K
Q
K
K
P
Honey Bee
Apis mellifera
XP_001121695
205
22930
S177
L
E
K
N
R
S
V
S
L
Q
P
V
Q
S
N
Nematode Worm
Caenorhab. elegans
P34443
207
23677
T184
S
R
G
N
L
S
P
T
E
R
P
N
G
N
S
Sea Urchin
Strong. purpuratus
XP_780973
198
22635
S174
L
E
K
R
R
T
M
S
L
H
L
E
T
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13856
272
30372
N249
V
P
K
S
G
S
S
N
R
T
G
I
S
A
T
Red Bread Mold
Neurospora crassa
Q01387
229
25331
V184
V
E
K
A
F
Y
D
V
V
K
Q
L
R
K
Q
Conservation
Percent
Protein Identity:
100
86.4
78.3
93.2
N.A.
98.9
41.7
N.A.
82.4
93.4
41.7
41.7
N.A.
42.2
71.7
39.1
79.4
Protein Similarity:
100
89.9
90.4
94.7
N.A.
100
61.8
N.A.
91.9
96.9
61.8
61.3
N.A.
63.3
79.5
52.1
89.4
P-Site Identity:
100
20
66.6
100
N.A.
100
0
N.A.
80
100
20
20
N.A.
6.6
53.3
6.6
66.6
P-Site Similarity:
100
40
80
100
N.A.
100
26.6
N.A.
86.6
100
40
40
N.A.
26.6
60
33.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.9
36.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.2
50.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
7
0
0
0
0
0
0
0
13
7
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
7
0
0
0
0
38
0
0
0
% D
% Glu:
0
57
7
0
7
0
0
7
13
0
0
7
0
7
7
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
0
7
0
0
0
0
0
7
7
63
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
7
7
13
0
0
0
0
0
32
7
0
0
0
% I
% Lys:
0
0
57
0
7
7
7
13
0
13
7
0
13
69
38
% K
% Leu:
63
0
0
0
7
0
0
0
50
7
7
7
0
0
0
% L
% Met:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
19
7
19
0
7
0
7
0
7
0
7
7
% N
% Pro:
0
7
0
0
0
0
7
7
7
13
19
7
0
0
13
% P
% Gln:
0
7
7
13
0
0
0
0
0
38
7
13
7
0
7
% Q
% Arg:
7
13
13
50
50
7
13
0
7
7
0
0
7
0
13
% R
% Ser:
7
0
0
7
0
19
13
44
7
0
7
0
7
7
7
% S
% Thr:
7
0
7
0
0
32
0
13
13
7
0
7
7
0
7
% T
% Val:
19
13
0
0
0
0
44
7
7
7
19
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _