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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DIRAS2 All Species: 45.15
Human Site: T39 Identified Species: 66.22
UniProt: Q96HU8 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HU8 NP_060064.2 199 22485 T39 F R E S Y I P T V E D T Y R Q
Chimpanzee Pan troglodytes XP_001142084 196 21944 T39 F R E S Y I P T V E D T Y R Q
Rhesus Macaque Macaca mulatta XP_001099006 198 22268 T39 F R D T Y I P T I E D T Y R Q
Dog Lupus familis XP_541313 208 23428 T48 F R E S Y I P T V E D T Y R Q
Cat Felis silvestris
Mouse Mus musculus Q5PR73 199 22479 T39 F R E S Y I P T V E D T Y R Q
Rat Rattus norvegicus Q62636 184 20779 Y40 D P T I E D S Y R K Q V E V D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513649 198 22370 T39 F R E T Y I P T I E D T Y R Q
Chicken Gallus gallus XP_423026 199 22563 T39 F R E S Y I P T I E D T Y R Q
Frog Xenopus laevis Q7ZXH7 184 20815 S39 Y D P T I E D S Y R K Q V E V
Zebra Danio Brachydanio rerio Q6TEN1 184 20809 S39 Y D P T I E D S Y R K Q V E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08645 184 20845 Y40 D P T I E D S Y R K Q V E V D
Honey Bee Apis mellifera XP_001121695 205 22930 T39 F R E S Y I P T I E D T Y R Q
Nematode Worm Caenorhab. elegans P34443 207 23677 T45 F P E R Y E S T I E D Q H S K
Sea Urchin Strong. purpuratus XP_780973 198 22635 T39 F R E C Y I P T I E D T Y R Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P13856 272 30372 K117 P M V L I G N K A D L I N E R
Red Bread Mold Neurospora crassa Q01387 229 25331 T40 F V E T Y D P T I E D S Y R K
Conservation
Percent
Protein Identity: 100 86.4 78.3 93.2 N.A. 98.9 41.7 N.A. 82.4 93.4 41.7 41.7 N.A. 42.2 71.7 39.1 79.4
Protein Similarity: 100 89.9 90.4 94.7 N.A. 100 61.8 N.A. 91.9 96.9 61.8 61.3 N.A. 63.3 79.5 52.1 89.4
P-Site Identity: 100 100 80 100 N.A. 100 0 N.A. 86.6 93.3 0 0 N.A. 0 93.3 40 86.6
P-Site Similarity: 100 100 100 100 N.A. 100 6.6 N.A. 100 100 20 20 N.A. 6.6 100 60 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.9 36.6
Protein Similarity: N.A. N.A. N.A. N.A. 49.2 50.6
P-Site Identity: N.A. N.A. N.A. N.A. 0 60
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 86.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 13 7 0 0 19 13 0 0 7 69 0 0 0 13 % D
% Glu: 0 0 63 0 13 19 0 0 0 69 0 0 13 19 0 % E
% Phe: 69 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 0 0 13 19 57 0 0 44 0 0 7 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 7 0 13 13 0 0 0 13 % K
% Leu: 0 0 0 7 0 0 0 0 0 0 7 0 0 0 0 % L
% Met: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 7 0 0 0 0 0 7 0 0 % N
% Pro: 7 19 13 0 0 0 63 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 13 19 0 0 57 % Q
% Arg: 0 57 0 7 0 0 0 0 13 13 0 0 0 63 7 % R
% Ser: 0 0 0 38 0 0 19 13 0 0 0 7 0 7 0 % S
% Thr: 0 0 13 32 0 0 0 69 0 0 0 57 0 0 0 % T
% Val: 0 7 7 0 0 0 0 0 25 0 0 13 13 13 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 0 0 0 69 0 0 13 13 0 0 0 63 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _