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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIRAS2
All Species:
39.7
Human Site:
T43
Identified Species:
58.22
UniProt:
Q96HU8
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HU8
NP_060064.2
199
22485
T43
Y
I
P
T
V
E
D
T
Y
R
Q
V
I
S
C
Chimpanzee
Pan troglodytes
XP_001142084
196
21944
T43
Y
I
P
T
V
E
D
T
Y
R
Q
V
I
S
C
Rhesus Macaque
Macaca mulatta
XP_001099006
198
22268
T43
Y
I
P
T
I
E
D
T
Y
R
Q
V
I
S
C
Dog
Lupus familis
XP_541313
208
23428
T52
Y
I
P
T
V
E
D
T
Y
R
Q
V
I
S
C
Cat
Felis silvestris
Mouse
Mus musculus
Q5PR73
199
22479
T43
Y
I
P
T
V
E
D
T
Y
R
Q
V
I
S
C
Rat
Rattus norvegicus
Q62636
184
20779
V44
E
D
S
Y
R
K
Q
V
E
V
D
A
Q
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513649
198
22370
T43
Y
I
P
T
I
E
D
T
Y
R
Q
V
I
S
C
Chicken
Gallus gallus
XP_423026
199
22563
T43
Y
I
P
T
I
E
D
T
Y
R
Q
V
I
S
C
Frog
Xenopus laevis
Q7ZXH7
184
20815
Q43
I
E
D
S
Y
R
K
Q
V
E
V
D
G
Q
Q
Zebra Danio
Brachydanio rerio
Q6TEN1
184
20809
Q43
I
E
D
S
Y
R
K
Q
V
E
V
D
G
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08645
184
20845
V44
E
D
S
Y
R
K
Q
V
E
V
D
G
Q
Q
C
Honey Bee
Apis mellifera
XP_001121695
205
22930
T43
Y
I
P
T
I
E
D
T
Y
R
Q
V
I
S
C
Nematode Worm
Caenorhab. elegans
P34443
207
23677
Q49
Y
E
S
T
I
E
D
Q
H
S
K
H
I
A
A
Sea Urchin
Strong. purpuratus
XP_780973
198
22635
T43
Y
I
P
T
I
E
D
T
Y
R
Q
V
I
S
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13856
272
30372
I121
I
G
N
K
A
D
L
I
N
E
R
V
I
S
V
Red Bread Mold
Neurospora crassa
Q01387
229
25331
S44
Y
D
P
T
I
E
D
S
Y
R
K
Q
V
V
I
Conservation
Percent
Protein Identity:
100
86.4
78.3
93.2
N.A.
98.9
41.7
N.A.
82.4
93.4
41.7
41.7
N.A.
42.2
71.7
39.1
79.4
Protein Similarity:
100
89.9
90.4
94.7
N.A.
100
61.8
N.A.
91.9
96.9
61.8
61.3
N.A.
63.3
79.5
52.1
89.4
P-Site Identity:
100
100
93.3
100
N.A.
100
6.6
N.A.
93.3
93.3
0
0
N.A.
6.6
93.3
33.3
93.3
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
100
6.6
6.6
N.A.
13.3
100
60
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.9
36.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.2
50.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
0
0
0
7
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
69
% C
% Asp:
0
19
13
0
0
7
69
0
0
0
13
13
0
0
0
% D
% Glu:
13
19
0
0
0
69
0
0
13
19
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
0
7
13
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% H
% Ile:
19
57
0
0
44
0
0
7
0
0
0
0
69
0
7
% I
% Lys:
0
0
0
7
0
13
13
0
0
0
13
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
63
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
13
19
0
0
57
7
13
25
13
% Q
% Arg:
0
0
0
0
13
13
0
0
0
63
7
0
0
0
0
% R
% Ser:
0
0
19
13
0
0
0
7
0
7
0
0
0
63
0
% S
% Thr:
0
0
0
69
0
0
0
57
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
25
0
0
13
13
13
13
63
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
69
0
0
13
13
0
0
0
63
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _