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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIRAS2
All Species:
32.12
Human Site:
Y101
Identified Species:
47.11
UniProt:
Q96HU8
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HU8
NP_060064.2
199
22485
Y101
L
E
E
L
K
P
I
Y
E
Q
I
C
E
I
K
Chimpanzee
Pan troglodytes
XP_001142084
196
21944
Y101
L
E
E
L
K
P
I
Y
E
Q
I
C
E
I
K
Rhesus Macaque
Macaca mulatta
XP_001099006
198
22268
Y101
L
E
E
L
G
P
I
Y
K
L
I
V
Q
I
K
Dog
Lupus familis
XP_541313
208
23428
Y110
L
E
E
L
K
P
I
Y
E
Q
I
C
E
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5PR73
199
22479
Y101
L
E
E
L
K
P
I
Y
E
Q
I
C
E
I
K
Rat
Rattus norvegicus
Q62636
184
20779
R102
D
L
R
E
Q
I
L
R
V
K
D
T
D
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513649
198
22370
Y101
L
E
E
L
Q
P
I
Y
E
Q
I
C
Q
I
K
Chicken
Gallus gallus
XP_423026
199
22563
Y101
L
E
E
L
K
P
I
Y
E
Q
I
C
Q
I
K
Frog
Xenopus laevis
Q7ZXH7
184
20815
L101
Q
D
L
R
E
Q
I
L
R
V
K
D
T
D
D
Zebra Danio
Brachydanio rerio
Q6TEN1
184
20809
L101
Q
D
L
R
E
Q
I
L
R
V
K
D
T
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08645
184
20845
R102
D
L
R
E
Q
I
L
R
V
K
D
T
D
D
V
Honey Bee
Apis mellifera
XP_001121695
205
22930
W101
L
E
E
L
R
P
I
W
A
I
I
R
E
L
K
Nematode Worm
Caenorhab. elegans
P34443
207
23677
Y107
F
E
M
C
S
N
I
Y
E
K
I
V
R
T
Y
Sea Urchin
Strong. purpuratus
XP_780973
198
22635
Y101
L
E
E
L
K
P
I
Y
D
I
I
R
E
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13856
272
30372
R179
S
V
A
V
K
D
A
R
N
Q
S
Q
Q
F
S
Red Bread Mold
Neurospora crassa
Q01387
229
25331
H102
F
A
R
I
K
K
F
H
H
Q
I
Q
R
V
K
Conservation
Percent
Protein Identity:
100
86.4
78.3
93.2
N.A.
98.9
41.7
N.A.
82.4
93.4
41.7
41.7
N.A.
42.2
71.7
39.1
79.4
Protein Similarity:
100
89.9
90.4
94.7
N.A.
100
61.8
N.A.
91.9
96.9
61.8
61.3
N.A.
63.3
79.5
52.1
89.4
P-Site Identity:
100
100
66.6
100
N.A.
100
0
N.A.
86.6
93.3
6.6
6.6
N.A.
0
60
33.3
80
P-Site Similarity:
100
100
80
100
N.A.
100
26.6
N.A.
100
100
20
20
N.A.
26.6
80
40
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.9
36.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.2
50.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
7
0
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
38
0
0
0
% C
% Asp:
13
13
0
0
0
7
0
0
7
0
13
13
13
25
13
% D
% Glu:
0
63
57
13
13
0
0
0
44
0
0
0
38
0
0
% E
% Phe:
13
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% F
% Gly:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
13
75
0
0
13
69
0
0
50
0
% I
% Lys:
0
0
0
0
50
7
0
0
7
19
13
0
0
0
63
% K
% Leu:
57
13
13
57
0
0
13
13
0
7
0
0
0
7
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
57
0
0
0
0
0
0
0
0
0
% P
% Gln:
13
0
0
0
19
13
0
0
0
50
0
13
25
0
0
% Q
% Arg:
0
0
19
13
7
0
0
19
13
0
0
13
13
0
0
% R
% Ser:
7
0
0
0
7
0
0
0
0
0
7
0
0
0
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
13
13
7
0
% T
% Val:
0
7
0
7
0
0
0
0
13
13
0
13
0
7
13
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
57
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _