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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DIRAS2 All Species: 36.97
Human Site: Y8 Identified Species: 54.22
UniProt: Q96HU8 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HU8 NP_060064.2 199 22485 Y8 M P E Q S N D Y R V A V F G A
Chimpanzee Pan troglodytes XP_001142084 196 21944 Y8 M P E Q S N D Y R V A V F G A
Rhesus Macaque Macaca mulatta XP_001099006 198 22268 Y8 M P E Q S N D Y R V V V F G A
Dog Lupus familis XP_541313 208 23428 Y17 M P E Q S N D Y R V A V F G A
Cat Felis silvestris
Mouse Mus musculus Q5PR73 199 22479 Y8 M P E Q S N D Y R V A V F G A
Rat Rattus norvegicus Q62636 184 20779 L9 R E Y K L V V L G S G G V G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513649 198 22370 Y8 M P E Q S N D Y R V V V F G A
Chicken Gallus gallus XP_423026 199 22563 Y8 M P E Q S N D Y R V V V F G A
Frog Xenopus laevis Q7ZXH7 184 20815 V8 M R E Y K L V V L G S G G V G
Zebra Danio Brachydanio rerio Q6TEN1 184 20809 V8 M R E Y K L V V L G S G G V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08645 184 20845 L9 R E Y K I V V L G S G G V G K
Honey Bee Apis mellifera XP_001121695 205 22930 Y8 M P E Q S N D Y R V V V F G A
Nematode Worm Caenorhab. elegans P34443 207 23677 R14 S N R Q S L N R K V A V M G Y
Sea Urchin Strong. purpuratus XP_780973 198 22635 Y8 M P E Q S N D Y R V V V F G A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P13856 272 30372 D86 L L V Y S V T D R Q S L E E L
Red Bread Mold Neurospora crassa Q01387 229 25331 Y9 V G N K Q V L Y K L V V L G D
Conservation
Percent
Protein Identity: 100 86.4 78.3 93.2 N.A. 98.9 41.7 N.A. 82.4 93.4 41.7 41.7 N.A. 42.2 71.7 39.1 79.4
Protein Similarity: 100 89.9 90.4 94.7 N.A. 100 61.8 N.A. 91.9 96.9 61.8 61.3 N.A. 63.3 79.5 52.1 89.4
P-Site Identity: 100 100 93.3 100 N.A. 100 6.6 N.A. 93.3 93.3 13.3 13.3 N.A. 6.6 93.3 40 93.3
P-Site Similarity: 100 100 93.3 100 N.A. 100 13.3 N.A. 93.3 93.3 20 20 N.A. 13.3 93.3 53.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.9 36.6
Protein Similarity: N.A. N.A. N.A. N.A. 49.2 50.6
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 20
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 32 0 0 0 57 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 57 7 0 0 0 0 0 0 7 % D
% Glu: 0 13 69 0 0 0 0 0 0 0 0 0 7 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 57 0 0 % F
% Gly: 0 7 0 0 0 0 0 0 13 13 13 25 13 82 13 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 19 13 0 0 0 13 0 0 0 0 0 13 % K
% Leu: 7 7 0 0 7 19 7 13 13 7 0 7 7 0 7 % L
% Met: 69 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 7 7 0 0 57 7 0 0 0 0 0 0 0 0 % N
% Pro: 0 57 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 63 7 0 0 0 0 7 0 0 0 0 0 % Q
% Arg: 13 13 7 0 0 0 0 7 63 0 0 0 0 0 0 % R
% Ser: 7 0 0 0 69 0 0 0 0 13 19 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % T
% Val: 7 0 7 0 0 25 25 13 0 63 38 69 13 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 13 19 0 0 0 63 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _