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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM41A
All Species:
13.64
Human Site:
S133
Identified Species:
23.08
UniProt:
Q96HV5
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HV5
NP_542383.1
264
29665
S133
F
G
K
Q
L
V
V
S
Y
F
P
D
K
V
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095986
264
29629
S133
F
G
K
Q
L
V
V
S
Y
F
P
D
K
V
A
Dog
Lupus familis
XP_545235
264
29643
S133
F
G
K
Q
L
V
V
S
Y
F
P
D
K
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8U2
264
29351
S133
F
G
K
Q
L
V
I
S
Y
F
P
D
K
V
A
Rat
Rattus norvegicus
Q5FVN2
291
32493
F141
F
L
S
I
L
S
G
F
L
Y
P
F
P
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513862
323
36410
N141
R
L
F
P
M
T
P
N
W
F
L
N
F
A
S
Chicken
Gallus gallus
Q5ZIL6
269
30250
F119
F
L
S
I
L
S
G
F
L
Y
P
F
P
L
A
Frog
Xenopus laevis
Q5U4K5
278
31193
F128
F
L
S
I
L
S
G
F
L
Y
P
F
P
L
A
Zebra Danio
Brachydanio rerio
Q502G2
281
31489
K150
F
G
K
H
H
I
V
K
L
F
P
D
K
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VX39
320
35815
F169
F
L
S
I
L
L
G
F
L
Y
K
F
P
I
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O62126
246
27484
C120
S
A
T
G
A
A
I
C
Y
T
I
S
K
L
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326733
249
27160
A118
V
A
L
V
V
F
T
A
T
A
G
A
S
S
C
Maize
Zea mays
NP_001141234
254
27619
I125
C
Y
F
L
S
K
M
I
G
K
P
L
V
F
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L586
287
32120
A154
F
V
L
V
V
L
N
A
T
A
G
A
C
S
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.8
92.4
N.A.
89
29.8
N.A.
59.7
30.4
30.5
59.7
N.A.
29
N.A.
29.9
N.A.
Protein Similarity:
100
N.A.
99.2
95.8
N.A.
92
52.2
N.A.
65.9
55
53.2
72.5
N.A.
49
N.A.
52.2
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
26.6
N.A.
6.6
26.6
26.6
66.6
N.A.
20
N.A.
13.3
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
40
N.A.
40
40
40
73.3
N.A.
40
N.A.
26.6
N.A.
Percent
Protein Identity:
33.7
32.9
N.A.
33.1
N.A.
N.A.
Protein Similarity:
53.7
51.8
N.A.
52.2
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
13.3
13.3
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
8
8
0
15
0
15
0
15
0
8
58
% A
% Cys:
8
0
0
0
0
0
0
8
0
0
0
0
8
0
15
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
36
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
72
0
15
0
0
8
0
29
0
43
0
29
8
8
8
% F
% Gly:
0
36
0
8
0
0
29
0
8
0
15
0
0
0
0
% G
% His:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
29
0
8
15
8
0
0
8
0
0
8
0
% I
% Lys:
0
0
36
0
0
8
0
8
0
8
8
0
43
0
0
% K
% Leu:
0
36
15
8
58
15
0
0
36
0
8
8
0
29
0
% L
% Met:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
8
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
8
0
0
8
0
0
0
65
0
29
0
0
% P
% Gln:
0
0
0
29
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
29
0
8
22
0
29
0
0
0
8
8
15
15
% S
% Thr:
0
0
8
0
0
8
8
0
15
8
0
0
0
0
8
% T
% Val:
8
8
0
15
15
29
29
0
0
0
0
0
8
36
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
36
29
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _